Doughty Austin C V, Hoover Ashley R, Layton Elivia, Murray Cynthia K, Howard Eric W, Chen Wei R
Biophotonics Research Laboratory, Center for Interdisciplinary Biomedical Education and Research, College of Mathematics and Science, University of Central Oklahoma, Edmond, OH 73034, USA.
Department of Mathematics and Statistics, College of Mathematics and Science, University of Central Oklahoma, Edmond, OH 73034, USA.
Materials (Basel). 2019 Mar 7;12(5):779. doi: 10.3390/ma12050779.
As a result of their unique compositions and properties, nanomaterials have recently seen a tremendous increase in use for novel cancer therapies. By taking advantage of the optical absorption of near-infrared light, researchers have utilized nanostructures such as carbon nanotubes, gold nanorods, and graphene oxide sheets to enhance photothermal therapies and target the effect on the tumor tissue. However, new uses for nanomaterials in targeted cancer therapy are coming to light, and the efficacy of photothermal therapy has increased dramatically. In this work, we review some of the current applications of nanomaterials to enhance photothermal therapy, specifically as photothermal absorbers, drug delivery vehicles, photoimmunological agents, and theranostic tools.
由于其独特的组成和性质，纳米材料最近在新型癌症治疗中的应用急剧增加。通过利用近红外光的光吸收特性，研究人员已利用碳纳米管、金纳米棒和氧化石墨烯片等纳米结构来增强光热疗法并靶向作用于肿瘤组织。然而，纳米材料在靶向癌症治疗中的新用途正在不断涌现，光热疗法的疗效也显著提高。在这项工作中，我们回顾了纳米材料目前在增强光热疗法方面的一些应用，特别是作为光热吸收剂、药物递送载体、光免疫制剂和诊疗工具。
