Department of Internal Medicine and Center for Tobacco Research, Comprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH.
Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD.
Nicotine Tob Res. 2021 Mar 19;23(4):760-764. doi: 10.1093/ntr/ntaa211.
To examine whether changes in select measures of e-cigarette puffing topography are associated with changes in smoking behavior.
Sixteen current cigarette smokers were instructed to completely switch from smoking combustible cigarettes to using e-cigarettes over a 2-week period. The study was completed in the Southern Midwestern region of the United States. Measures included demographics, smoking history, and cigarette dependence, as well as baseline and 2-week follow-up self-reported cigarettes per day, cigarette craving and urges, exhaled carbon monoxide readings, and e-cigarette usage data (puff number, puffing time, and average puff duration) collected via the e-cigarette built-in puff counter.
Over the 2-week switching period, participants significantly reduced their cigarettes per day (~80% reduction, p < .0001). Although the number of e-cigarette puffs/day remained relatively stable (p > .05), the average total e-cigarette daily puffing time increased significantly (p = .001). Users' average puff duration increased by 91 ms/puff/d (p < .001). The percentage decrease in cigarettes smoked per day was significantly and directly related to the slope of subjects' average puff duration over time (r(13) = .62, p = .01), such that as cigarettes per day decreased, puff duration increased. Self-reported smoking urges remained relatively stable from baseline to the end of the 2-week period (p > .05).
Among smokers switching to an e-cigarette, greater increases in e-cigarette puff duration was associated with greater reductions in cigarette smoking.
The current study is one of the first to examine changes in smokers' e-cigarette puffing behavior and associated changes in cigarette consumption as they attempt to completely switch to e-cigarettes. During a 2-week switching period, participants reduced their cigarettes per day. Moreover, although e-cigarette puffs per day remained relatively stable, users' average puff duration increased significantly. Greater increases in e-cigarette puff duration were associated with greater reductions in cigarette smoking. Understanding how to effectively use an e-cigarette to best reduce and eventually quit smoking will be necessary as smokers increasingly turn to these products to facilitate possible cessation.
本研究旨在探讨电子烟吸烟特征的某些指标变化是否与吸烟行为变化相关。
16 名当前吸烟的吸烟者被要求在两周内完全从吸食可燃香烟转换为使用电子烟。该研究在美国南部中西部地区进行。研究中包括人口统计学、吸烟史和香烟依赖度,以及基线和两周随访时的自我报告的每日香烟量、吸烟渴求感和冲动感、呼出的一氧化碳读数,以及通过电子烟内置吸烟计数器收集的电子烟使用数据(吸烟次数、吸烟时间和平均吸烟时间)。
在两周的转换期间,参与者的每日香烟量显著减少(~80%的减少,p <.0001)。尽管电子烟每日吸烟次数相对稳定(p >.05),但平均总电子烟每日吸烟时间显著增加(p =.001)。使用者的平均吸烟时间增加了 91 毫秒/次/天(p <.001)。每天吸烟量的减少与受试者平均吸烟时间随时间的斜率呈显著正相关(r(13) =.62,p =.01),即随着每天吸烟量的减少,吸烟时间增加。从基线到两周结束时,自我报告的吸烟冲动感相对稳定(p >.05)。
在转换为电子烟的吸烟者中,电子烟吸烟时间的增加与香烟吸烟量的减少显著相关。
本研究是首次研究吸烟者在试图完全转换为电子烟时电子烟吸烟行为的变化及其与香烟消费变化的关系。在两周的转换期间,参与者减少了每日吸烟量。此外,尽管电子烟每日吸烟次数相对稳定,但用户的平均吸烟时间显著增加。电子烟吸烟时间的增加与香烟吸烟量的减少显著相关。随着吸烟者越来越多地转向这些产品来促进可能的戒烟,了解如何有效地使用电子烟来最大限度地减少和最终戒烟将是必要的。