Alnuqaydan Abdullah M, Rah Bilal
Medical Biotechnology, Applied Medical Sciences College, Qassim University, Al-Qassim, Saudi Arabia.
Department of Immunology and Molecular Medicine, Sher-i-Kasmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India.
Curr Pharm Biotechnol. 2019;20(4):285-292. doi: 10.2174/1389201020666190318120103.
Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in combination with other plant extracts against different ailments since ancient times.
Electronic database survey via Pubmed, Google Scholar, Researchgate, Scopus and Science Direct were used to review the scientific inputs until October 2018, by searching appropriate keywords. Literature related to pharmacological activities of T. articulata, Tamarix species, phytochemical analysis of T. articulata, biological activities of T. articulata extracts. All of these terms were used to search the scientific literature associated with T. articulata; the dosage of extract, route of administration, extract type, and in-vitro and in-vivo model.
Numerous reports revealed that T. articulata contains a wide spectrum of phytochemical(s), which enables it to have a wide window of biological properties. Owing to the presence of high content of phytochemical compounds like polyphenolics and flavonoids, T. articulata is a potential source of antioxidant, anti-inflammatory and antiproliferative properties. In view of these pharmacological properties, T. articulata could be a potential drug candidate to treat various clinical conditions including cancer in the near future.
In this review, the spectrum of phytochemical(s) has been summarized for their pharmacological properties and the mechanisms of action, and the possible potential therapeutic applications of this plant against various diseases discussed.
节枝柽柳,在阿拉伯地区通常被称为柽柳或阿萨尔,属于柽柳科物种。它是一种重要的盐生药用植物,也是多酚类植物化学物质的良好来源。在传统医学中,自古以来节枝柽柳提取物就被单独或与其他植物提取物联合用于治疗各种疾病。
通过搜索适当的关键词,利用PubMed、谷歌学术、Researchgate、Scopus和科学Direct等电子数据库进行调查,以回顾截至2018年10月的科学资料。与节枝柽柳的药理活性、柽柳属物种、节枝柽柳的植物化学分析、节枝柽柳提取物的生物活性相关的文献。所有这些术语都用于搜索与节枝柽柳相关的科学文献;提取物的剂量、给药途径、提取物类型以及体外和体内模型。
大量报告显示,节枝柽柳含有多种植物化学物质,这使其具有广泛的生物学特性。由于含有高含量的多酚类和黄酮类等植物化学化合物,节枝柽柳具有抗氧化、抗炎和抗增殖特性的潜在来源。鉴于这些药理特性,节枝柽柳在不久的将来可能成为治疗包括癌症在内的各种临床疾病的潜在候选药物。
在本综述中,总结了植物化学物质的光谱及其药理特性和作用机制,并讨论了该植物对各种疾病可能的潜在治疗应用。