Alcohol Research Group, Public Health Institute, Emeryville, CA, USA.
Addiction. 2019 Jul;114(7):1303-1308. doi: 10.1111/add.14603. Epub 2019 Apr 29.
Including a low-intensity blood collection method in population-based alcohol studies would advance our ability to study biological mechanisms related to alcohol. However, the likelihood of participation in such a blood collection method remains understudied. This study's primary aims were to (1) estimate the return rate of mail-in, self-administered dried blood spot (saDBS) samples in national surveys and (2) test correlates of returning a sample.
Re-contact of all eligible participants from two telephone, population-based alcohol surveys followed by χ tests and multivariate logistic regression analysis.
Non-institutionalized US population in all 50 states and Washington, DC.
Adults aged 18+ who reported drinking at least one alcoholic beverage in the past 12 months (assessed 2017-18). Contact was made with 680 eligible participants, and 257 consented.
The return rate of saDBS samples was defined as the proportion of returned samples among those who were eligible and contacted. Key correlates examined were gender, age, race/ethnicity and education.
Among the 680 eligible people contacted, 179 (26.3%) returned a saDBS sample. Blacks [odds ratio (OR) = 0.58, 95% confidence interval (CI) = 0.35-0.95], Latinos (OR = 0.40, 95% CI = 0.23-0.69) and those with a high school education or less (OR = 0.50, 95% CI = 0.31-0.81).
The likelihood of participating in mail-in, self-administered dried blood spot (saDBS) sampling among drinkers in the US general population appears low, and blacks, Latinos and people with lower levels of education appear less likely to provide a saDBS sample compared with whites and people with higher levels of education.
在基于人群的酒精研究中纳入一种低强度的采血方法，将提高我们研究与酒精相关的生物学机制的能力。然而，这种采血方法的参与率仍有待研究。本研究的主要目的是：（1）估计全国性酒精调查中邮寄、自我管理的干血斑（saDBS）样本的回收率；（2）测试样本返还的相关因素。
对两次电话酒精调查中所有符合条件的参与者进行重新联系，然后进行 χ 检验和多变量逻辑回归分析。
美国所有 50 个州和华盛顿特区的非机构化人群。
年龄在 18 岁及以上、过去 12 个月内报告至少饮用过一种含酒精饮料的成年人（2017-18 年评估）。与 680 名符合条件的参与者进行了联系，其中 257 人同意参与。
saDBS 样本的回收率定义为符合条件且联系的样本中返回样本的比例。检查的主要相关因素是性别、年龄、种族/民族和教育程度。
在联系的 680 名符合条件的人中，有 179 人（26.3%）返回了 saDBS 样本。黑人[比值比（OR）=0.58，95%置信区间（CI）=0.35-0.95]、拉丁裔（OR=0.40，95%CI=0.23-0.69）和高中及以下学历者（OR=0.50，95%CI=0.31-0.81）的可能性较低。
美国普通人群中饮酒者参与邮寄、自我管理的干血斑（saDBS）采样的可能性似乎较低，与白人相比，黑人、拉丁裔和受教育程度较低的人提供 saDBS 样本的可能性较小，而受教育程度较高的人则较少。
