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人体眼部细胞中 5.8GHz 电磁场暴露对微核形成、DNA 链断裂和热休克蛋白表达的影响。

Effects of Exposure to 5.8 GHz Electromagnetic Field on Micronucleus Formation, DNA Strand Breaks, and Heat Shock Protein Expressions in Cells Derived From Human Eye.

出版信息

IEEE Trans Nanobioscience. 2019 Apr;18(2):257-260. doi: 10.1109/TNB.2019.2905491. Epub 2019 Mar 15.

DOI:10.1109/TNB.2019.2905491
PMID:30892224
Abstract

In the near future, electrification will be introduced to heavy-duty vehicles and passenger cars. However, the wireless power transfer (WPT) requires high energy levels, and the suitability of various types of WPT systems must be assessed. This paper describes a method for solving technical and safety issues associated with this technology. We exposed human corneal epithelial (HCE-T) cells derived from the human eye to 5.8-GHz electromagnetic fields for 24 h. We observed no statistically significant increase in micronucleus (MN) frequency in cells exposed to a 5.8-GHz field at 1 mW/cm (the general public level in ICNIRP) relative to sham-exposed or incubator controls. Similarly, the DNA strand breaks, and the expression of heat shock protein (Hsp) Hsp27, Hsp70, and Hsp 90α exhibited no statistically significant effects as a result of exposure. These results indicate that the exposure to 5.8-GHz electromagnetic fields at 1 mW/cm for 24 h has little or no effect on micronucleus formation, DNA strand breaks, and Hsp expression in human eye cells.

摘要

在不久的将来,重型车辆和乘用车将实现电气化。然而,无线电能传输(WPT)需要高能量水平,因此必须评估各种类型的 WPT 系统的适用性。本文描述了一种解决与该技术相关的技术和安全问题的方法。我们将源自人眼的人角膜上皮(HCE-T)细胞暴露于 5.8-GHz 电磁场中 24 小时。我们观察到,与假暴露或孵育对照相比,暴露于 1 mW/cm(ICNIRP 的公众普遍水平)5.8-GHz 场的细胞中微核(MN)频率没有统计学上的显著增加。同样,由于暴露,DNA 链断裂以及热休克蛋白(Hsp)Hsp27、Hsp70 和 Hsp90α 的表达也没有表现出统计学上的显著影响。这些结果表明,在 1 mW/cm 下暴露于 5.8-GHz 电磁场 24 小时对人眼细胞中的微核形成、DNA 链断裂和 Hsp 表达几乎没有影响或没有影响。

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