Chen Y, Li W, Yu S
Br Med J (Clin Res Ed). 1986 Aug 2;293(6542):303-6. doi: 10.1136/bmj.293.6542.303.
An association was sought between passive smoking and inpatient admissions for respiratory illness in 1058 children born between 1 June and 31 December 1981 and living in the neighborhoods of Nan-Jing Western Road and Yan-An Western Road in Jing-An District, Shanghai. The admission rate for first episodes of respiratory illness was positively correlated with the total daily cigarette consumption of family members during the children's first 18 months of life. The relative risk of developing a first episode of respiratory illness was 1.80 for children living in families including people who smoked 10 or more cigarettes a day compared with those living in non-smoking families. Multiple logistic regression analysis showed that the effect of passive smoking on inpatient admission for respiratory illness was independent of the child's birth weight, type of feeding, father's education, size of the home, and chronic respiratory disease among adults in the family. The adjusted odds ratios compared with the non-smoking group were 1.17 in families smoking 1.9 cigarettes daily and 1.89 in families smoking 10 or more cigarettes daily. These data suggest that exposure to household cigarette smoke of children in early life increases the risk of severe respiratory illness.
在1981年6月1日至12月31日出生、居住于上海静安区南京西路和延安西路附近的1058名儿童中,研究了被动吸烟与呼吸系统疾病住院之间的关联。儿童呼吸系统疾病首次发作的住院率与儿童出生后头18个月家庭成员的每日吸烟总量呈正相关。与生活在无烟家庭的儿童相比,生活在家庭成员每天吸烟10支或更多的家庭中的儿童发生首次呼吸系统疾病的相对风险为1.80。多因素logistic回归分析表明,被动吸烟对呼吸系统疾病住院的影响独立于儿童的出生体重、喂养方式、父亲的教育程度、家庭规模以及家庭中成年人的慢性呼吸系统疾病。与无烟组相比,每日吸烟1.9支家庭的校正比值比为1.17,每日吸烟10支或更多家庭的校正比值比为1.89。这些数据表明,儿童在生命早期接触家庭香烟烟雾会增加患严重呼吸系统疾病的风险。