Colley J R
Br Med J. 1974 Apr 27;2(5912):201-4. doi: 10.1136/bmj.2.5912.201.
A study of respiratory symptoms in 2,426 schoolchildren aged 6-14 years was carried out in Aylesbury, Buckinghamshire, in 1971. The prevalence of cough in the children was associated with the parents' smoking habits; prevalence was lowest where both parents were non-smokers, highest where both parents smoked, and lay between these two levels where only one parent smoked. A close association was found between parents' and children's respiratory symptoms that was independent of parents' smoking habits. There was no suggestion that exposure to the cigarette smoke generated when parents smoked had any more than a small effect upon the child's respiratory symptoms. While the sharing of genetic susceptibility between parents and children is a factor, therefore, cross infection, particularly in the families where parents smoke, is an important element in the association.
1971年,在白金汉郡艾尔斯伯里对2426名6至14岁的学童进行了一项呼吸道症状研究。儿童咳嗽的患病率与父母的吸烟习惯有关;父母均不吸烟的儿童患病率最低,父母均吸烟的儿童患病率最高,只有一方父母吸烟的儿童患病率介于两者之间。研究发现,父母和孩子的呼吸道症状之间存在密切关联,且这种关联与父母的吸烟习惯无关。没有迹象表明,父母吸烟时产生的香烟烟雾对孩子的呼吸道症状有显著影响。因此,虽然父母与孩子之间遗传易感性的共享是一个因素,但交叉感染,尤其是在父母吸烟的家庭中,是这种关联中的一个重要因素。