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睡眠障碍相关性头痛。

Sleep disorder-related headaches.

机构信息

IRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Neurology-Sleep Disorders Centre, Milan, Italy.

"Vita-Salute" San Raffaele University, Milan, Italy.

出版信息

Neurol Sci. 2019 May;40(Suppl 1):107-113. doi: 10.1007/s10072-019-03837-z.

DOI:10.1007/s10072-019-03837-z
PMID:30906963
Abstract

Migraine with and without aura, cluster headache, hypnic headache, and paroxysmal hemicranias are each reported as intrinsically related to sleep. Chronic migraine, chronic tension-type headache, and medication overuse headache may cause sleep disturbance. Otherwise, both headache and sleep disorder may be manifestations of a same systemic dysfunction. There is a vicious cycle linking sleep disorders and migraine. The poor quality or poor duration of sleep could be a trigger of migraine attack and migraineurs with poor sleep reported a higher headache frequency. Moreover, coping behaviors of migraineurs (e.g., going to sleep early to relieve migraine attacks) can be factors precipitating and perpetuating sleep disturbances themselves. During cluster headache, patients report a poor quality of sleep correlated with the amount of daylight. In particular, it was demonstrated that melatonin levels have influences on cluster headache attacks. Concerning the pathophysiology of hypnic headache, it has been hypothesized a possible role of obstructive sleep apnea in triggering nocturnal attacks: an increased number of apnea episodes has been reported in hypnic headache patients, but a lack of a temporal correlation of headache attacks with the drop of oxygen saturation has been observed. Tension-type headache is the most common headache with sleep dysregulation (lack of sleep or oversleeping) frequently reported as a triggering factor for acute attacks: management of sleep disturbances seems crucial in this form of headache.

摘要

有先兆和无先兆偏头痛、丛集性头痛、催眠性头痛和阵发性半边头痛,均被报道与睡眠密切相关。慢性偏头痛、慢性紧张型头痛和药物过度使用性头痛可能导致睡眠障碍。否则,头痛和睡眠障碍可能是同一全身功能障碍的表现。睡眠障碍和偏头痛之间存在恶性循环。睡眠质量差或持续时间短可能是偏头痛发作的诱因,睡眠不佳的偏头痛患者报告头痛发作频率更高。此外,偏头痛患者的应对行为(例如,早睡以缓解偏头痛发作)也可能是引发和持续睡眠障碍的因素。在丛集性头痛期间,患者报告睡眠质量差与白天的日光量有关。特别是,已经证明褪黑素水平对丛集性头痛发作有影响。关于催眠性头痛的病理生理学,有人假设阻塞性睡眠呼吸暂停可能在引发夜间发作中起作用:已经报道在催眠性头痛患者中,呼吸暂停发作次数增加,但观察到头痛发作与氧饱和度下降之间没有时间相关性。紧张型头痛是最常见的伴有睡眠失调(睡眠不足或过度睡眠)的头痛,常被报道为急性发作的诱因:在这种类型的头痛中,管理睡眠障碍似乎至关重要。

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Therapeutic role of melatonin in migraine prophylaxis: A systematic review.褪黑素在偏头痛预防中的治疗作用:一项系统评价。
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Variables Associated With the Use of Prophylactic Amitriptyline Treatment in Patients With Tension-type Headache.紧张型头痛患者预防性使用阿米替林治疗的相关变量。
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Chiari Malformation Type 1 in Adults.成人 Chiari 畸形 1 型。
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