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[具体物质名称]在缓解轻度认知障碍方面的潜力：一项综述。 （注：原文中“in”前面缺少具体物质，这里翻译时保留了原文结构，等待补充完整物质名称后能更准确翻译）

The potential of in alleviating mild cognitive impairment: a review.

作者信息

Gao Huimin, Lu Hanyu, Fang Nengqiao, Su Jinsong, Li Rui, Wang Wenjun, Zhang Yi

机构信息

College of Pharmacy and Meishan Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

School of Ethmic Medicine, Chengdu University of Taditional Chinese Medicine, Chengdu, Sichuan, China.

出版信息

Front Pharmacol. 2024 Oct 18;15:1484040. doi: 10.3389/fphar.2024.1484040. eCollection 2024.

DOI:10.3389/fphar.2024.1484040
PMID:39494343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11528016/
Abstract

Retz. (, ཨ་རུ་ར།) is highly utilized in ethnic medicine. Its medicinal value is gradually being recognized and shows great potential in the improvement of mild cognitive impairment (MCI) disorders. Tibetan medicine theory classifies this type of disease as one of the "Jie Xie Syndrome (བརྗེད་བྱེད།)." The role of in such diseases has been increasingly studied. This work aimed to elucidate the research progress of in alleviating MCI. The review offers a critical update on the current understanding of the effect of on MCI and highlights new opportunities for exploring its therapeutic potential. This review discusses the role of in alleviating MCI and provides a comprehensive overview of the traditional medicinal uses, chemical composition, toxicology, and quality control aspects of . This review covers chemical constituents and active constituents targeting MCI, such as flavonoids, which can alleviate MCI, primarily through its antioxidative, anti-inflammatory, and neuroprotective properties. shows potential as a natural medicine for the treatment and prevention of MCI. As an important part of ethnomedicinal resources, this work offers valuable insights for future research on -containing ethnomedicines. Research on traditional drug treatments, optimized treatment standards, improved societal knowledge about MCI, and development of an early detection system is essential to the diagnosis and treatment of MCI. These efforts will provide better treatment resources for patients with MCI.

摘要

Retz.（藏药阿如拉）在民族医学中被广泛应用。其药用价值逐渐得到认可，在改善轻度认知障碍（MCI）疾病方面显示出巨大潜力。藏医学理论将这类疾病归类为“杰协症（བརྗེད་བྱེད།）”之一。Retz.在这类疾病中的作用已得到越来越多的研究。这项工作旨在阐明Retz.在缓解MCI方面的研究进展。该综述对目前对Retz.对MCI影响的理解进行了重要更新，并突出了探索其治疗潜力的新机会。本综述讨论了Retz.在缓解MCI中的作用，并全面概述了Retz.的传统药用、化学成分、毒理学和质量控制方面。本综述涵盖了Retz.的化学成分以及针对MCI的活性成分，如黄酮类化合物，其可主要通过抗氧化、抗炎和神经保护特性来缓解MCI。Retz.作为治疗和预防MCI的天然药物具有潜力。作为民族医药资源的重要组成部分，这项工作为未来对含Retz.民族药物的研究提供了有价值的见解。对传统药物治疗、优化治疗标准、提高社会对MCI的认识以及开发早期检测系统的研究对于MCI的诊断和治疗至关重要。这些努力将为MCI患者提供更好的治疗资源。

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