线粒体逆行信号与肿瘤微环境中的代谢改变。
Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment.
机构信息
Department of Physiology, College of Medicine, Gachon University, Incheon 21999, Korea.
Department of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Korea.
出版信息
Cells. 2019 Mar 22;8(3):275. doi: 10.3390/cells8030275.
Abstract
This review explores the molecular mechanisms that may be responsible for mitochondrial retrograde signalling related metabolic reprogramming in cancer and host cells in the tumour microenvironment and provides a summary of recent updates with regard to the functional modulation of diverse cells in the tumour microenvironment.
摘要
本文探讨了可能导致肿瘤微环境中与线粒体逆行信号相关的代谢重编程的分子机制，并总结了有关肿瘤微环境中不同细胞功能调节的最新进展。
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