Kawai Hidetsugu, Matsushita Hiromichi, Kawakami Shohei, Furuya Daisuke, Shiraiwa-Hara Sawako, Ichiki Akifumi, Hara Ryujiro, Aoyama Yasuyuki, Ogiya Daisuke, Suzuki Rikio, Machida Shinichiro, Onizuka Makoto, Shirasugi Yukari, Ogawa Yoshiaki, Kawada Hiroshi, Nakamura Naoya, Ando Kiyoshi
J Clin Exp Hematop. 2019;59(1):34-39. doi: 10.3960/jslrt.18038.
Composite lymphoma (CL) is defined as the occurrence of two distinct types of lymphoma within the same patient. Most cases of CL involve Hodgkin and non-Hodgkin lymphomas or two distinct types of B-cell lymphomas; true CL is a composite B-cell and T-cell lymphoma, and is rare. We herein report a case involving concurrent extranodal NK/T-cell lymphoma, nasal-type and diffuse large B-cell lymphoma, which has not been previously reported. As the mechanisms and treatments of composite B-cell and T-cell lymphomas are unclear, further studies are required to improve the prognosis.
复合淋巴瘤(CL)定义为同一患者体内出现两种不同类型的淋巴瘤。大多数CL病例涉及霍奇金淋巴瘤和非霍奇金淋巴瘤或两种不同类型的B细胞淋巴瘤;真正的CL是一种B细胞和T细胞复合淋巴瘤,较为罕见。我们在此报告一例同时发生结外NK/T细胞淋巴瘤、鼻型和弥漫性大B细胞淋巴瘤的病例,此前尚未见报道。由于复合B细胞和T细胞淋巴瘤的发病机制及治疗方法尚不清楚,需要进一步研究以改善预后。