Tegelberg-Stassen M J, van der Willigen A H, van der Hoek J C, Wagenvoort J H, van Vliet H J, van Klingeren B, van Joost T, Michel M F, Stolz E
Eur J Clin Microbiol. 1986 Aug;5(4):395-8. doi: 10.1007/BF02075693.
One hundred and twenty-three female patients suffering from uncomplicated urogenital gonorrhoea were treated in a double blind randomised trial with either 200 mg enoxacin (one capsule of 200 mg, one of placebo) or 400 mg enoxacin (two capsules of 200 mg). The cure rate in the 46 evaluable patients in the 400 mg group was 100%, and in the 40 evaluable patients in the 200 mg group 98.7%. Minor side effects such as nausea, headache and skin rash occurred in three of 109 evaluable patients (2.8%). The minimum inhibitory concentration of enoxacin for the Neisseria gonorrhoeae strains isolated varied between 0.03 and 0.12 mcg/ml. Enoxacin would seem to be a very effective drug in the treatment of uncomplicated urogenital gonorrhoea in female patients.
123名患有单纯性泌尿生殖系统淋病的女性患者参与了一项双盲随机试验，她们被随机分为两组，分别接受200毫克依诺沙星（一粒200毫克胶囊加一粒安慰剂）或400毫克依诺沙星（两粒200毫克胶囊）的治疗。400毫克组46名可评估患者的治愈率为100%，200毫克组40名可评估患者的治愈率为98.7%。109名可评估患者中有3人（2.8%）出现了恶心、头痛和皮疹等轻微副作用。分离出的淋病奈瑟菌菌株对依诺沙星的最低抑菌浓度在0.03至0.12微克/毫升之间。依诺沙星似乎是治疗女性单纯性泌尿生殖系统淋病的一种非常有效的药物。
