Service de Physique Médicale et Radioprotection, Groupement Hospitaliers Est, Hospices Civils de Lyon, Bron.
Clin Nucl Med. 2019 Jul;44(7):568-569. doi: 10.1097/RLU.0000000000002554.
We evaluated the reproducibility of I-ioflupane (I-FP-CIT) SPECT with shorter scan times using a CZT camera. One hundred ninety-nine I-FP-CIT SPECT scans obtained with standard scan time (30 minutes) were truncated to provide 24-, 18-, and 15-minute study simulations. Striatal binding ratios were automatically calculated and remained stable for all series. At 15 minutes, only 10 of 398 striata (2.5%) showed statistically significant different striatal binding ratios compared with reference series. These series were reviewed by 2 operators, and a perfect agreement was found for each patient. Therefore, CZT camera allows a 2-fold scan time reduction in I-FP-CIT SPECT.
我们使用 CZT 相机评估了使用更短扫描时间的碘[123I]-β-正丙基碘托比胍（I-FP-CIT）SPECT 的可重复性。将 199 次使用标准扫描时间（30 分钟）获得的 I-FP-CIT SPECT 扫描截断为 24 分钟、18 分钟和 15 分钟的研究模拟。纹状体结合比自动计算，并在所有系列中保持稳定。在 15 分钟时，与参考系列相比，仅 398 个纹状体中的 10 个（2.5%）显示出统计学上显著不同的纹状体结合比。这两个系列由 2 位操作人员进行了回顾，并且发现每位患者的结果都完全一致。因此，CZT 相机允许 I-FP-CIT SPECT 的扫描时间减少两倍。
