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基于 2012-2013 年韩国国家健康和营养检查调查的巧克力食用与中年人群听力损失和耳鸣的关联。

Association of Chocolate Consumption with Hearing Loss and Tinnitus in Middle-Aged People Based on the Korean National Health and Nutrition Examination Survey 2012⁻2013.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul 03080, Korea.

Medical Research Collaborating Center, Seoul National University Hospital, Seoul 03080, Korea.

出版信息

Nutrients. 2019 Mar 30;11(4):746. doi: 10.3390/nu11040746.

Abstract

Chocolate, which is produced from cocoa, exerts antioxidant and anti-inflammatory effects that ameliorate neurodegenerative diseases. We hypothesized that chocolate consumption would protect against hearing loss and tinnitus. We evaluated the hearing and tinnitus data, as well as the chocolate consumption, of middle-aged participants (40⁻64 years of age) of the 2012⁻2013 Korean National Health and Nutrition Examination Survey. All of the subjects underwent a medical interview, physical examination, audiological evaluation, tinnitus questionnaire, and nutrition examination. A total of 3575 subjects 40⁻64 years of age were enrolled. The rate of any hearing loss (unilateral or bilateral) in the subjects who consumed chocolate (26.78% (338/1262)) was significantly lower than that in those who did not (35.97% (832/2313)) ( < 0.001). Chocolate consumption was independently associated with low odds of any hearing loss (adjusted odds ratio = 0.83, 95% confidence interval = 0.70 to 0.98, = 0.03). Moreover, the severity of hearing loss was inversely correlated with the frequency of chocolate consumption. In contrast to chocolate, there was no association between hearing loss and the consumption of sweet products without cocoa. Chocolate consumption was also not associated with tinnitus or tinnitus-related annoyance. Our results suggest that a chocolate-based diet may protect middle-aged people from hearing loss.

摘要

巧克力由可可制成,具有抗氧化和抗炎作用,可以改善神经退行性疾病。我们假设巧克力的摄入可以预防听力损失和耳鸣。我们评估了 2012-2013 年韩国国家健康和营养检查调查中中年参与者(40-64 岁)的听力和耳鸣数据以及巧克力的摄入量。所有参与者都接受了医学访谈、体检、听力评估、耳鸣问卷和营养检查。共有 3575 名 40-64 岁的受试者被纳入研究。摄入巧克力的受试者(26.78%(338/1262))发生任何听力损失(单侧或双侧)的比例明显低于未摄入巧克力的受试者(35.97%(832/2313))(<0.001)。巧克力的摄入与较低的任何听力损失风险独立相关(调整后的优势比=0.83,95%置信区间=0.70 至 0.98,=0.03)。此外,听力损失的严重程度与巧克力的摄入频率呈反比。与巧克力不同的是,甜食(不含可可)的摄入与听力损失之间没有关联。巧克力的摄入也与耳鸣或耳鸣相关的烦恼无关。我们的结果表明,基于巧克力的饮食可能有助于保护中年人免受听力损失的影响。

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