Ukleja Anna, Andrzejewska Marta, Skroński Michał K, Ławiński Michał, Włodarek Dariusz, Korba Michał, Nyckowski Paweł, Słodkowski Maciej
Department of Clinical Dietetics, Medical University of Warsaw, Warsaw, Poland.
Department of General, Gastroenterological, and Oncological Surgery, Medical University of Warsaw, Warsaw, Poland.
Prz Gastroenterol. 2019;14(1):62-68. doi: 10.5114/pg.2019.83427. Epub 2019 Mar 12.
The metabolism of the body is a complicated process. The most important organ of the organism that affects the intensity of changes is the liver. An effective treatment method of primary and metastatic tumours is a partial resection of the organ. The analysis of changes in the body composition of patients undergoing this type of treatment allows identification of problems coexisting with the underlying disease.
To evaluate changes in the parameters of body composition and the amount of resting metabolism.
The study group consisted of 87 patients who underwent resection of changes in the liver or thermoablation of focal lesions during hospitalisation.
Analysis of the data showed that the surgical intervention contributes to a statistically significant ( < 0.05) decrease in the value of the phase angle. A significant increase was noted within the extra cellular water content. The amount of resting metabolism in the postoperative period did not differ significantly; however, there was an upward trend in women and a downward trend in men.
Surgical resection of lesions aimed at extending the survival of patients are performed more and more often, while the consequences of these operations are not sufficiently known. The adverse effect of resection treatments on body composition parameters, mainly imaged by decreasing the phase angle value, should be minimised. Effects on metabolism remain ambiguous because no significant changes have been demonstrated in the postoperative period.
身体的新陈代谢是一个复杂的过程。影响变化强度的机体最重要器官是肝脏。原发性和转移性肿瘤的一种有效治疗方法是对该器官进行部分切除。对接受此类治疗的患者身体成分变化进行分析,有助于识别与基础疾病并存的问题。
评估身体成分参数和静息代谢量的变化。
研究组由87例住院期间接受肝脏病变切除或局灶性病变热消融的患者组成。
数据分析表明,手术干预导致相角值在统计学上显著降低(<0.05)。细胞外含水量显著增加。术后静息代谢量无显著差异;然而,女性有上升趋势,男性有下降趋势。
旨在延长患者生存期的病变手术切除越来越频繁,而这些手术的后果尚不完全清楚。切除治疗对身体成分参数的不利影响,主要表现为相角值降低,应降至最低。对代谢的影响仍不明确,因为术后未显示出显著变化。