Abd Elmoneim Abeer A, Al Hawsawi Zakaria M, Mahmoud Badr Z, Bukhari Abdullah A, Almulla Abdulmalik A, Sonbol Abdullah M, Makhdoum Anas M
Pediatric Department, Taibah University, Al-Madinah Al-Munawarah, Kingdom of Saudi Arabia. E-mail.
Saudi Med J. 2019 Apr;40(4):401-404. doi: 10.15537/smj.2019.4.24049.
To highlight the causes of hospitalization among sickle cell diseased (SCD) children in Al-Madinah Al-Munawarah, Saudi Arabia.
A retrospective study conducted at the Maternity and Children's Hospital, Al-Madinah Al-Munawarah, Saudi Arabia. A data of 739 SCD children admitted to the hematology/oncology unit between October 2010 and September 2015 were collected. The collected data were analyzed using an independent t test and a Chi square test as appropriate.
Approximately 49% of the studied children were presented by acute painful crisis. Acute chest syndrome was reported in 20.9%. Infection was the cause of admission in 17.5%, and acute anemia was reported in 8.1% of the studied patients. No significant difference of the reported clinical manifestations by patients' gender. Children aged <12 years showed significantly high frequency of acute chest syndrome (ACS) (26.5%), while acute painful crisis (66.4%) was significantly more frequent among children aged ≥12 years.
This study revealed high rate of hospitalization of SCD children because of acute painful crisis, ACS, infection, and anemia. These admissions causes could potentially be continuously assessed to minimize the rate of hospitalization.
强调沙特阿拉伯麦地那市镰状细胞病（SCD）患儿的住院原因。
在沙特阿拉伯麦地那市的妇幼医院进行一项回顾性研究。收集了2010年10月至2015年9月期间收治于血液科/肿瘤科的739例SCD患儿的数据。所收集的数据根据情况使用独立t检验和卡方检验进行分析。
约49%的研究患儿因急性疼痛危象就诊。急性胸综合征的报告发生率为20.9%。感染是17.5%的患儿的入院原因，8.1%的研究患者报告有急性贫血。所报告的临床表现按患者性别无显著差异。年龄<12岁的儿童急性胸综合征（ACS）发生率显著较高（26.5%），而年龄≥12岁的儿童急性疼痛危象（66.4%）的发生率显著更高。
本研究显示SCD患儿因急性疼痛危象、ACS、感染和贫血而住院的比例较高。这些入院原因可能需要持续评估，以尽量降低住院率。
