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跆拳道训练后二十八烷醇对脂质的改善及氧化应激的降低作用

Improvement of Lipids and Reduction of Oxidative Stress With Octacosanol After Taekwondo Training.

作者信息

Lee Sang-Ho, Scott Steven D, Pekas Elizabeth J, Lee Jeong-Gi, Park Song-Young

出版信息

Int J Sports Physiol Perform. 2019 Oct 1;14(9):1297-1303. doi: 10.1123/ijspp.2018-0704.

DOI:10.1123/ijspp.2018-0704
PMID:30958045
Abstract

PURPOSE

Athletes in combat sports undergo rapid changes in body weight prior to competition in order to gain a size advantage over their opponent. However, these large weight changes with concomitant high-intensity exercise training create poor lipid profiles and high levels of oxidative stress, which can be detrimental to health and sport performance. Therefore, the purpose of this study was to investigate the ability of the nutritional supplement octacosanol to combat the physiological detriments that occur in taekwondo players during rapid weight loss with high-intensity exercise training.

METHODS

A total of 26 male taekwondo players were randomly divided into 2 groups: An experimental group performed a 5% weight-loss and taekwondo training program with 40-mg octacosanol intake (OCT; n = 13) for 6 d, and a control group performed the same weight-loss and taekwondo training program with a placebo (CON; n = 13).

RESULTS

There were significant (P < .05) group × time interactions for low-density lipoprotein and triglycerides, which significantly decreased (Δ18 [5] mg/dL and Δ80 [7] mg/dL, respectively), and high-density lipoprotein, which significantly increased (Δ10 [7] mg/dL), in the OCT group compared with the CON group. There were also significant (P < .05) group × time interactions for superoxide dismutase (SOD), glutathione peroxidase (GPx), and malondialdehyde (MDA), with SOD increasing (Δ226 [121] U/gHb) in the OCT group, while GPx decreased (Δ20 [13] U/gHb) and MDA increased (Δ72 [0.04] nmol/mL) in the CON group.

CONCLUSION

These results suggest that octacosanol may be a beneficial supplement to protect against the poor cholesterol levels and oxidative stress that occurs during taekwondo training.

摘要

目的

格斗运动项目的运动员在比赛前会快速改变体重,以获得相对于对手的体型优势。然而,这些伴随高强度运动训练的大幅度体重变化会导致血脂状况不佳以及氧化应激水平升高,这可能对健康和运动表现产生不利影响。因此,本研究的目的是调查营养补充剂二十八烷醇对抗跆拳道运动员在高强度运动训练导致快速减重期间所发生的生理损害的能力。

方法

总共26名男性跆拳道运动员被随机分为2组:实验组进行减重5%的跆拳道训练计划,并摄入40毫克二十八烷醇(OCT;n = 13),为期6天;对照组进行相同的减重和跆拳道训练计划,但服用安慰剂(CON;n = 13)。

结果

与CON组相比,OCT组的低密度脂蛋白和甘油三酯存在显著(P <.05)的组×时间交互作用,分别显著降低(分别为Δ18 [5] mg/dL和Δ80 [7] mg/dL),而高密度脂蛋白显著升高(Δ [7] mg/dL)。超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPx)和丙二醛(MDA)也存在显著(P <.05)的组×时间交互作用,OCT组的SOD增加(Δ226 [121] U/gHb),而CON组的GPx降低(Δ20 [13] U/gHb)且MDA增加(Δ72 [0.04] nmol/mL)。

结论

这些结果表明,二十八烷醇可能是一种有益的补充剂,可预防跆拳道训练期间出现的不良胆固醇水平和氧化应激。

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