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无烟烟草使用者唾液中可替宁浓度的决定因素

The Determinants of Salivary Cotinine Concentration in Smokeless Tobacco Users.

作者信息

Mahmoodabad Sayed Saeed Mazloomy, Jadgal Mohammad Saeed, Zareban Iraj, Zadeh Hossein Fallah

机构信息

Social Determinants of Health Research Center, Department of Health Education & Promotion, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

出版信息

Open Access Maced J Med Sci. 2019 Mar 13;7(5):810-815. doi: 10.3889/oamjms.2019.174. eCollection 2019 Mar 15.

DOI:10.3889/oamjms.2019.174
PMID:30962846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6447324/
Abstract

BACKGROUND

Smokeless tobacco products due to their high nicotine content are highly addictive and ultimately lead to an increased risk of oral cavity, laryngeal and oesophagal cancer.

AIM

This research was conducted with the aim of assessing the relationship between the salivary cotinine concentration and demographic characteristics and smokeless tobacco use for the first time in tradespeople in Chabahar, Iran.

METHODS

This descriptive cross-sectional study was conducted on 150 different tradespeople using smokeless tobacco in Chabahar who were selected through simple random sampling in 2018. In addition to the salivary cotinine measurement, data were collected using a researcher-made questionnaire with demographic and behavioural items. The data obtained were analysed in SPSS-16 using descriptive and inferential statistics.

RESULTS

The mean salivary cotinine score was 887.7 ± 180.7 in men and 611.2 ± 139.7 in women, making for a significant intergroup difference (P = 0.043). The mean salivary cotinine score was higher in those who used two or more smokeless tobacco products compared to those who used one type of tobacco, and a significant difference was observed between the type of smokeless tobacco used and the salivary cotinine score in the participants (P = 0.005).

CONCLUSION

Based on the results of the regression analysis, the type of smokeless tobacco used was a strong predictor of the concentration of salivary cotinine in the participants. It is, therefore, necessary for the government to adopt appropriate policies and take educational measures to reduce the vending and use of these substances.

摘要

背景

无烟烟草制品因其高尼古丁含量而极易上瘾,并最终导致口腔、喉和食管癌风险增加。

目的

本研究旨在首次评估伊朗恰巴哈尔商人唾液可替宁浓度与人口统计学特征及无烟烟草使用之间的关系。

方法

2018年,通过简单随机抽样,对恰巴哈尔150名使用无烟烟草的不同商人进行了这项描述性横断面研究。除测量唾液可替宁外,还使用研究人员自制的包含人口统计学和行为项目的问卷收集数据。所得数据在SPSS-16中使用描述性和推断性统计进行分析。

结果

男性唾液可替宁平均得分是887.7±180.7,女性为611.2±139.7,组间差异显著(P = 0.043)。与使用一种烟草的人相比,使用两种或更多种无烟烟草制品的人唾液可替宁平均得分更高,且参与者使用的无烟烟草类型与唾液可替宁得分之间存在显著差异(P = 0.005)。

结论

基于回归分析结果,使用的无烟烟草类型是参与者唾液可替宁浓度的有力预测指标。因此,政府有必要采取适当政策并采取教育措施,以减少这些物质的销售和使用。

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本文引用的文献

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Determinants of Salivary Cotinine among Smokeless Tobacco Users: A Cross-Sectional Survey in Bangladesh.无烟烟草使用者唾液可替宁的影响因素:孟加拉国的一项横断面调查
PLoS One. 2016 Aug 9;11(8):e0160211. doi: 10.1371/journal.pone.0160211. eCollection 2016.
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Utility and cutoff value of hair nicotine as a biomarker of long-term tobacco smoke exposure, compared to salivary cotinine.与唾液可替宁相比,头发尼古丁作为长期烟草烟雾暴露生物标志物的效用及临界值。
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