Functional Genomics of : Strategies and Progress.

has been used for the production of traditional fermentation and has promising potential to produce primary and secondary metabolites. Due to the tough cell walls and high drug resistance of , functional genomic characterization studies are relatively limited. The exploitation of selection markers and genetic transformation methods are critical for improving fermentative strains. In this review, we describe the genome sequencing of various strains. Recently developed selection markers and transformation strategies are also described in detail, and the advantages and disadvantages of transformation methods are presented. Lastly, we introduce the recent progress on highlighted topics in functional genomics including conidiation, protein secretion and expression, and secondary metabolites, which will be beneficial for improving the application of to industrial production.