Minimally Invasive Techniques Research Center in Women, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2019 Feb 1;22(2):71-75.
Gender identity disorder (GID) is associated with various adverse health outcomes as well as psychiatric problems. Quality of life (QOL) in patients after surgery is an important issue, as some cases report dissatisfaction and regret after surgery. The present study compared QOL in female-to-male (FTM) GID patients before and after gender reassignment surgery (GRS) in an Iranian population. In the present study, 42 natal female patients with Gender Disorder diagnosis, who were referred to the Fertility Research Center of Tehran University of Medical Sciences for GRS from December 2014 to December 2015, were prospectively recruited.
The demographic characteristics, including age, body mass index (BMI), occupational and marital status, educational level, and family support were recorded. Then, participants were asked to complete the Persian version of the 36-Item Short Form Health Survey (SF-36) questionnaire under supervision of the researcher, once at baseline and once 6 months after surgery.
The changes in SF-36 scores and association with the demographic variables were then evaluated using SPSS 16 at significance level of 0.05. Mean age of patients was 34.17 ± 5.58 years with a mean BMI of 43.14 ± 6.91 kg/m2 . Most were single (54.8%), had primary school education (50.5%), and acceptable family support (59.5%). Total mean score of QOL significantly improved from 26.43±6.81 to 37.52 ± 8.67 (P < 0.001), 6 months after surgery and also in all domains (P < 0.001), although the increase in emotional problem was not statistically significant (P = 0.05).
In conclusion, as the results of the present study highlight, FTM GD patients have a low QOL before surgery that is significantly improved after surgery.
性别认同障碍（GID）与各种不良健康结果以及精神问题有关。手术后患者的生活质量（QOL）是一个重要问题，因为有些病例报告手术后不满意和后悔。本研究比较了伊朗人群中女性到男性（FTM）GID 患者手术前后的 QOL。在本研究中，前瞻性招募了 2014 年 12 月至 2015 年 12 月期间因 GRS 而被转诊至德黑兰大学医学科学生育研究中心的 42 名患有性别障碍诊断的天生女性患者。
记录人口统计学特征，包括年龄、体重指数（BMI）、职业和婚姻状况、教育水平和家庭支持。然后，在研究人员的监督下，让参与者填写 36 项简短健康调查问卷（SF-36）的波斯语版本，一次在基线时，一次在手术后 6 个月时。
使用 SPSS 16 评估 SF-36 评分的变化及其与人口统计学变量的相关性，显著性水平为 0.05。患者的平均年龄为 34.17 ± 5.58 岁，平均 BMI 为 43.14 ± 6.91kg/m2。大多数是单身（54.8%），具有小学教育程度（50.5%）和可接受的家庭支持（59.5%）。手术后 6 个月，生活质量总平均评分从 26.43±6.81 显著提高至 37.52 ± 8.67（P < 0.001），并且所有领域的评分都有所提高（P < 0.001），尽管情绪问题的增加没有统计学意义（P = 0.05）。
总之，正如本研究的结果所强调的那样，FTM GD 患者手术前的 QOL 较低，手术后明显改善。
