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哮喘死亡率:新西兰与英格兰的比较。

Asthma mortality: comparison between New Zealand and England.

作者信息

Sears M R, Rea H H, Rothwell R P, O'Donnell T V, Holst P E, Gillies A J, Beaglehole R

出版信息

Br Med J (Clin Res Ed). 1986 Nov 22;293(6558):1342-5. doi: 10.1136/bmj.293.6558.1342.

DOI:10.1136/bmj.293.6558.1342
PMID:3098342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1342054/
Abstract

Causes for the high mortality from asthma in New Zealand were investigated by comparing deaths from asthma in caucasian subjects aged 15-64 in New Zealand with those from asthma in the same age group in two regions in England. There were no significant differences in the accuracy of death certification. The verified asthma mortality in New Zealand (4.2/100,000) was over twice that in England. Many characteristics of patients and management, including poor compliance with treatment and deficiencies in long term and emergency care, were qualitatively similar in the two countries. New Zealand had an apparently higher rate of non-preventable deaths from asthma, suggesting a greater severity of asthma in New Zealand. In both countries, however, most deaths were associated with poor assessment, underestimation of severity and inappropriate treatment (over-reliance on bronchodilators and underuse of systemic corticosteroids), and delays in obtaining help. A greater frequency of some of these deficiencies in management remains a possible additional explanation for part of the excess mortality in New Zealand.

摘要

通过比较新西兰15至64岁白种人哮喘死亡情况与英格兰两个地区同年龄组哮喘死亡情况,对新西兰哮喘高死亡率的原因进行了调查。死亡证明的准确性没有显著差异。新西兰经核实的哮喘死亡率(4.2/10万)是英格兰的两倍多。两国患者的许多特征及管理情况,包括治疗依从性差以及长期和急诊护理不足,在性质上相似。新西兰哮喘不可预防死亡的发生率明显较高,表明新西兰哮喘病情更严重。然而,在这两个国家,大多数死亡都与评估不佳、对严重程度估计不足、治疗不当(过度依赖支气管扩张剂和全身性皮质类固醇使用不足)以及寻求帮助延迟有关。管理中这些不足情况出现的频率更高,这仍然可能是新西兰部分超额死亡率的一个额外解释。

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本文引用的文献

1
Asthma prevalence in Tokelauan children in two environments.两种环境下托克劳儿童的哮喘患病率
Clin Allergy. 1980 Jan;10(1):71-5. doi: 10.1111/j.1365-2222.1980.tb02082.x.
2
Asthma mortality in Birmingham 1975-7: 53 deaths.1975 - 1977年伯明翰的哮喘死亡率:53例死亡。
Br Med J. 1980 Mar 8;280(6215):687-90. doi: 10.1136/bmj.280.6215.687.
3
Trends in sales of drugs for asthma in New Zealand, Australia, and the United Kingdom, 1975-81.1975 - 1981年新西兰、澳大利亚和英国哮喘药物销售趋势。
Br Med J (Clin Res Ed). 1984 Aug 11;289(6441):348-51. doi: 10.1136/bmj.289.6441.348.
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Asthma in New Zealand.新西兰的哮喘病
Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):374-7. doi: 10.1136/bmj.286.6362.374.
5
Has the change to beta-agonists combined with oral theophylline increased cases of fatal asthma?改用β受体激动剂联合口服茶碱是否增加了致命性哮喘的病例?
Lancet. 1981 Jun 6;1(8232):1235-7. doi: 10.1016/s0140-6736(81)92403-x.
6
Dose response of patients to oral corticosteroid treatment during exacerbations of asthma.哮喘急性发作期患者口服糖皮质激素治疗的剂量反应
Br Med J (Clin Res Ed). 1986 Apr 19;292(6527):1045-7. doi: 10.1136/bmj.292.6527.1045.
7
Asthma mortality in England and Wales: evidence for a further increase, 1974-84.英格兰和威尔士的哮喘死亡率:1974 - 1984年进一步上升的证据
Lancet. 1986 Aug 9;2(8502):323-6. doi: 10.1016/s0140-6736(86)90012-7.
8
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9
Asthma deaths in Cardiff 1963-74: 90 deaths outside hospital.1963年至1974年加的夫的哮喘死亡情况:90例死于院外。
Br Med J. 1976 Jun 19;1(6024):1493-5. doi: 10.1136/bmj.1.6024.1493.