Escola Superior Agrária, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.
Centro de Biotecnologia de Plantas da Beira Interior, 6001-909 Castelo Branco, Portugal.
Molecules. 2019 Apr 2;24(7):1283. doi: 10.3390/molecules24071283.
Aiton and its berries have been used in Chinese traditional medicine for around two thousand years. In the present study, berries harvested in two regions of Portugal were studied. Haemolytic activity and inhibition of oxidative haemolysis as well as the enzyme inhibitory activities (α-amylase enzyme and acetylcholinesterase) were assessed. Results suggest that the different biological activities varied according to the region where samples were collected. Results demonstrated that the sample obtained from region R1 was the most efficient extract for all parameters evaluated, presenting the lowest values of IC, 10.67 ± 0.46 μg/mL for the inhibition of erythrocyte oxidative haemolysis, 58.28 ± 3.77 μg/mL for the α-amylase enzyme and 67.67 ± 2.10 μg/mL for the acetylcholinesterase inhibition. berries may be an interesting source of compounds for use in the development of the therapeutic armamentarium for diseases where enzymatic disruption is believed to play a role.
Aiton 及其浆果在中国传统医学中已经使用了大约两千年。在本研究中，研究了在葡萄牙两个地区收获的浆果。评估了溶血活性和氧化溶血抑制以及酶抑制活性（α-淀粉酶酶和乙酰胆碱酯酶）。结果表明，不同的生物活性根据样品采集的区域而有所不同。结果表明，从 R1 区获得的样品对所有评估参数都是最有效的提取物，表现出最低的 IC 值，对红细胞氧化溶血的抑制作用为 10.67 ± 0.46 μg/mL，对α-淀粉酶的抑制作用为 58.28 ± 3.77 μg/mL，对乙酰胆碱酯酶的抑制作用为 67.67 ± 2.10 μg/mL。Aiton 浆果可能是一种有趣的化合物来源，可用于开发治疗疾病的药物，这些疾病被认为与酶的破坏有关。
