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骨质疏松症的诊断与治疗:骨科医生须知。

Diagnosis and Treatment of Osteoporosis: What Orthopaedic Surgeons Need to Know.

机构信息

From the Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA (Dr. Matzkin), the Department of Orthopaedics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (DeMaio), the Departments of Orthopaedic Surgery and Medicine, Brigham and Women's Hospital, Boston, MA (Charles), and the Department of Orthopaedics, Shriners Hospital for Children, Philadelphia, PA (Franklin).

出版信息

J Am Acad Orthop Surg. 2019 Oct 15;27(20):e902-e912. doi: 10.5435/JAAOS-D-18-00600.

Abstract

Osteoporosis, often called a silent disease, is a systemic condition of bone as a result of loss of bone mass and deterioration of its microarchitecture. The result is weakened bone, leading to an increased risk of fragility fractures. An estimated 9 million osteoporotic fractures occur every year worldwide. However, the true incidence of osteoporotic fractures is unknown because many are undetected. Astoundingly, this epidemic equates to an osteoporotic fracture every 3 seconds. Orthopaedic surgeons need to not only treat these fractures but also understand the underlying pathogenesis and risk factors to help prevent them. The management of osteoporosis is a critical part of musculoskeletal care. We must be familiar with the tools to assess osteoporosis and the treatments available, including risks and benefits. This review article is intended to deliver a review of the vast literature and provide the orthopaedic surgeon with the essential information necessary to manage the current osteoporosis epidemic.

摘要

骨质疏松症,通常被称为无声的疾病,是一种全身性的骨骼疾病,其特征是骨量减少和微观结构恶化。其结果是骨骼变弱,导致脆性骨折的风险增加。据估计,全世界每年有 900 万例骨质疏松性骨折。然而,由于许多骨折没有被发现,真正的骨质疏松性骨折发生率尚不清楚。令人震惊的是,这种流行病相当于每 3 秒钟就有一例骨质疏松性骨折。骨科医生不仅需要治疗这些骨折,还需要了解潜在的发病机制和危险因素,以帮助预防这些骨折。骨质疏松症的治疗是肌肉骨骼护理的重要组成部分。我们必须熟悉评估骨质疏松症的工具以及可用的治疗方法,包括风险和益处。这篇综述文章旨在对大量文献进行综述,并为骨科医生提供管理当前骨质疏松症流行所需的基本信息。

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