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在急诊科实施药物审查计划的效果。

The efficacy of a medication review programme conducted in an emergency department.

机构信息

Pharmacy Department, Hospital Universitario Príncipe de Asturias, Crta Alcalá-Meco s/n, 28805, Alcalá de Henares, Madrid, Spain.

Pharmacy Department, Hospital Son Llátzer, 07198, Palma, Illes Balears, Spain.

出版信息

Int J Clin Pharm. 2019 Jun;41(3):757-766. doi: 10.1007/s11096-019-00836-0. Epub 2019 Apr 26.

Abstract

Background Older age and inappropriate prescribing is related to a greater rate of emergency department visits and hospitalisations. Objective To assess the efficacy of an interprofessional collaboration programme in which a review of the medication of older patients seen in the emergency observation unit was carried out. Setting Emergency departments at four Spanish hospitals. Method Randomised, controlled study. Patients over 65 years of age presenting to the emergency department were randomised to a control or an intervention group. In the intervention group, a pharmacist reviewed the patients' chronic medication and identified any potentially inappropriate prescriptions based on the STOPP/START criteria. Each case was discussed with the emergency specialist and a recommendation to modify the treatment was sent to the general practitioner. Main outcome measure Rate of emergency visits and hospital admissions. Results The adjusted rate ratio of emergency visits and hospital admissions was 0.808 (95% CI 0.617 to 1.059) at 3 months, 0.888 (95% CI 0.696 to 1.134) at 6 months and 0.954 (95% CI 0.772 to 1.179) at 12 months. There was a statistically significant reduction at 3 months in two of the hospitals that participated in the study [adjusted rate ratio at 3 months was 0.452 (95% CI 0.222 to 0.923) in hospital 3 and 0.567 (95% CI 0.328 to 0.983) in hospital 4]. Conclusion Overall, the intervention did not reduce the number of emergency visits and hospital admissions. However, a significant effect was observed in centres were a high acceptance rate of treatment recommendations was achieved.

摘要

背景

年龄较大和不适当的处方与更高的急诊就诊率和住院率有关。

目的

评估一种多专业合作计划的效果,该计划对在急诊观察单元就诊的老年患者的药物进行审查。

地点

西班牙四家医院的急诊部门。

方法

随机对照研究。随机分配 65 岁以上就诊于急诊的患者进入对照组或干预组。在干预组中,药剂师审查患者的慢性药物,并根据 STOPP/START 标准确定任何潜在的不适当处方。每个病例都与急诊专家进行了讨论,并向全科医生发送了修改治疗方案的建议。

主要结果测量

急诊就诊率和住院率。

结果

调整后 3 个月、6 个月和 12 个月的急诊就诊率和住院率的比值比分别为 0.808(95%CI 0.617 至 1.059)、0.888(95%CI 0.696 至 1.134)和 0.954(95%CI 0.772 至 1.179)。有两所参与研究的医院在 3 个月时有显著下降[调整后的 3 个月比值比为医院 3 为 0.452(95%CI 0.222 至 0.923),医院 4 为 0.567(95%CI 0.328 至 0.983)]。

结论

总体而言,干预措施并未降低急诊就诊率和住院率。然而,在治疗建议接受率较高的中心,观察到了显著的效果。

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