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为什么患者想要或拒绝使用抗生素:动机清单。

Why patients want to take or refuse to take antibiotics: an inventory of motives.

机构信息

Jean-Jaurès University, CERPPS, Maison de la recherche, 5 allées Antonio Machado, 31058, Toulouse cedex 9, France.

University of Québec (TELUQ), 5800, rue Saint-Denis, Bureau 1105, Montréal, Québec, H2S 3L5, Canada.

出版信息

BMC Public Health. 2019 Apr 27;19(1):441. doi: 10.1186/s12889-019-6834-x.

DOI:10.1186/s12889-019-6834-x
PMID:31029110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6487028/
Abstract

BACKGROUND

Inappropriate use of antibiotics is a worldwide issue. In order to help public health institutions and each particular physician to change patterns of consumption among patients, it is important to understand better the reasons why people accept to take or refuse to take the antibiotic drugs. This study explored the motives people give for taking or refusing to take antibiotics.

METHODS

Four hundred eighteen adults filled out a 60-item questionnaire that consisted of assertions referring to reasons for which the person had taken antibiotics in the past and a 70-item questionnaire that listed reasons for which the person had sometimes refused to take antibiotics.

RESULTS

A six-factor structure of motives to take antibiotics was found: Appropriate Prescription, Protective Device, Enjoyment (antibiotics as a quick fix allowing someone to go out), Others' Pressure, Work Imperative, and Personal Autonomy. A four-factor structure of motives not to take antibiotics was found: Secondary Gain (through prolonged illness), Bacterial Resistance, Self-defense (the body is able to defend itself) and Lack of trust. Scores on these factors were related to participants' demographics and previous experience with antibiotics.

CONCLUSION

Although people are generally willing to follow their physician's prescription of antibiotics, a notable proportion of them report adopting behaviors that are beneficial to micro-organisms and, as a result, potentially detrimental to humans.

摘要

背景

抗生素的不恰当使用是一个全球性问题。为了帮助公共卫生机构和每位特定的医生改变患者的消费模式,了解人们接受或拒绝服用抗生素的原因非常重要。本研究探讨了人们服用或拒绝服用抗生素的动机。

方法

418 名成年人填写了一份 60 项的问卷,其中包含过去因何服用抗生素的陈述,以及一份 70 项的问卷,其中列出了有时拒绝服用抗生素的原因。

结果

发现了服用抗生素的六个因素结构:适当的处方、保护装置、享受(抗生素作为一种快速解决方法,让人可以外出)、他人的压力、工作需要和个人自主权。发现了不服用抗生素的四个因素结构:继发获益(通过延长疾病)、细菌耐药性、自我防御(身体能够自我防御)和缺乏信任。这些因素的得分与参与者的人口统计学特征和以前使用抗生素的经历有关。

结论

尽管人们通常愿意遵循医生开的抗生素处方,但相当一部分人报告说采取了对微生物有益、但对人类可能有害的行为。

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The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems.肠-脑轴:肠道微生物群、中枢神经系统和肠神经系统之间的相互作用。
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Lancet Infect Dis. 2014 Aug;14(8):742-750. doi: 10.1016/S1473-3099(14)70780-7. Epub 2014 Jul 9.
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