针刺联合草药与单纯草药治疗斑块状银屑病：一项系统评价方案

Acupuncture combined with herbal medicine versus herbal medicine alone for plaque psoriasis: a systematic review protocol.

作者信息

Xiao Shiju, Li Bo, Feng Shuo, Liu Cunzhi, Zhang Guangzhong

机构信息

Dermatology Department, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China.

Graduate School, Capital Medical University, Beijing 100069, China.

出版信息

Ann Transl Med. 2019 Mar;7(6):115. doi: 10.21037/atm.2018.09.17.

DOI:10.21037/atm.2018.09.17

PMID:31032270

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6465449/

Abstract

BACKGROUND

Psoriasis is a condition with a multifactorial etiopathogenesis worldwide, and plaque psoriasis, which is characterized by redness, thickness, and scaling, is the most common kind. Individuals living with psoriasis show low levels of life quality, and having fewer or less extensive lesions may improve spiritual and mental health. Therefore, our objective is to explore the effectiveness of acupuncture combined with herbal medicine for plaque psoriasis and to compare acupuncture combined with herbal medicine with herbal medicine alone.

METHODS

Databases including PubMed, MEDLINE, the Cochrane Library, Excerpta Medica (EMBASE), the Chinese Biomedical Literature Database (CBM), the China National Knowledge Infrastructure Database (CNKI), the Wanfang database and the Chinese Scientific Journal Database (VIP database) will be searched from inception to March 2018. We will employ hand searches, and grey literature will also be obtained. Only randomized controlled trials evaluating acupuncture combined with herbal medicine to treat plaque psoriasis in adults will be assessed. The Psoriasis Area and Severity Index score (PASI score), the itching index, the life quality scores, and the anxiety index will be the outcome measures. Two independent reviewers will select the articles included, assess the risk of bias and extract data according to the inclusion criteria. A third reviewer will resolve disagreements. The purpose of this study will be to identify the effect of acupuncture combined with herbal medicine on the lesions (PASI score), symptoms (itching index, life quality scores) and mental status (anxiety index) of the patients.

DISCUSSION

The meta-analysis will retrospectively examine current evidence regarding the effectiveness of the practice of acupuncture combined with herbal medicine to treat plaque psoriasis. This study may reveal, for the first time, an adjuvant therapy for psoriasis.

TRIAL REGISTRATION

As the study is a systematic review protocol, trial registration will not be necessary. An article containing the results will be published in a peer-reviewed journal and disseminated through scientific conferences.

摘要

背景

银屑病是一种在全球范围内病因多因素的疾病，斑块状银屑病是最常见的类型，其特征为发红、增厚和脱屑。银屑病患者的生活质量较低，皮损较少或范围较小可能会改善精神和心理健康。因此，我们的目的是探讨针灸联合中药治疗斑块状银屑病的有效性，并将针灸联合中药与单纯中药进行比较。

方法

检索包括PubMed、MEDLINE、Cochrane图书馆、医学文摘数据库（EMBASE）、中国生物医学文献数据库（CBM）、中国知网数据库（CNKI）、万方数据库和维普数据库（VIP数据库）在内的数据库，检索时间从建库至2018年3月。我们将进行手工检索，也会获取灰色文献。仅评估针灸联合中药治疗成人斑块状银屑病的随机对照试验将被纳入评估。银屑病面积和严重程度指数评分（PASI评分）、瘙痒指数、生活质量评分和焦虑指数将作为观察指标。两名独立的评审员将根据纳入标准选择纳入的文章、评估偏倚风险并提取数据。第三名评审员将解决分歧。本研究的目的是确定针灸联合中药对患者皮损（PASI评分）、症状（瘙痒指数、生活质量评分）和精神状态（焦虑指数）的影响。