Masmali Ali M, Alanazi Saud A, Alotaibi Abdullah G, Fagehi Raied, Abusharaha Ali, El-Hiti Gamal A
Cornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia,
Clin Ophthalmol. 2019 Apr 10;13:605-610. doi: 10.2147/OPTH.S201127. eCollection 2019.
The study aimed to investigate the acute effect of a single dose of green tea on the quality and quantity of tears in normal eye subjects.
Forty normal eye subjects (22 men and 18 women) aged 19-39 years were enrolled in the study. Also, an age matching control group (20 males and 20 females) was enrolled for comparison. McMonnies dry eye symptoms questionnaire and slit lamp were used for the exclusion criteria determination. Phenol red thread (PRT) test was performed on both eyes of each subject. A tear sample was collected from the lower tear meniscus of the right eye of each subject for the tear ferning (TF) test, which was performed before (30 minutes) and after (60 minutes) drinking green tea.
The median PRT measurement after green tea consumption was lower (median [IQR]=23.50 [8.00] mm) compared to that before consumption (median [IQR]=27.00 [8.75] mm). In contrast, the median TF grade was significantly higher following green tea consumption than that before consumption (median [IQR]=2.65 [1.23] vs 1.50 [0.88] mm, respectively). The results show that TF grades increased in 97.5%, and the red phenol thread scores decreased in 80% of the subjects after green tea consumption compared to those before consumption. The PRT readings and TF grades were significantly different (<0.05) before and after green tea consumption.
Drinking green tea could have a significant effect on the eye tear film quality. Tear quality appeared to decrease after green tea consumption.
本研究旨在调查单剂量绿茶对正常眼部受试者泪液质量和量的急性影响。
40名年龄在19 - 39岁的正常眼部受试者（22名男性和18名女性）参与了本研究。此外，招募了一个年龄匹配的对照组（20名男性和20名女性）进行比较。使用麦克莫尼斯干眼症状问卷和裂隙灯确定排除标准。对每个受试者的双眼进行酚红棉线（PRT）试验。从每个受试者右眼的下泪弯月面收集泪液样本进行泪液蕨样变（TF）试验，该试验在饮用绿茶前（30分钟）和饮用后（60分钟）进行。
饮用绿茶后的PRT测量中位数较低（中位数[四分位间距]=23.50[8.00]mm），而饮用前为（中位数[四分位间距]=27.00[8.75]mm）。相比之下，饮用绿茶后TF分级中位数显著高于饮用前（分别为中位数[四分位间距]=2.65[1.23]和1.50[0.88]mm）。结果显示，与饮用绿茶前相比，饮用后9
