Post Graduate Program in Parasite Biology, Ceuma University, São Luís, Brazil.
School of Medicine, Federal University of Maranhão, São Luís, Brazil.
Cranio. 2021 May;39(3):231-237. doi: 10.1080/08869634.2019.1607445. Epub 2019 May 1.
: To assess salivary biomarkers for dental caries susceptibility and mental stress in young adults with perceived facial pain.: Males and females who reported facial pain and pain-free controls participated in this study. Facial pain was investigated using the RDC/TMD. Unstimulated saliva was then collected for the evaluation of salivary flow rate (SFR), pH, counts, morning cortisol, and S-IgA.: Women with facial pain had significantly lower SFR values, and the facial pain group showed different correlations among biomarkers for caries susceptibility and cortisol levels when compared to controls. Notably, higher SFR values were associated with a lower likelihood of having facial pain.: Differences in SFR values, particularly in women, and markedly distinct interactions among the salivary biomarkers analyzed were observed between individuals with facial pain and pain-free controls. Hence, a connection between the dynamics of saliva, stress response, and facial pain perception might exist.
: 评估有感知面部疼痛的年轻成年人的唾液生物标志物与龋齿易感性和精神压力的关系。: 本研究纳入了报告面部疼痛和无痛对照的男性和女性。使用 RDC/TMD 调查面部疼痛。然后收集非刺激性唾液以评估唾液流速 (SFR)、pH 值、计数、晨皮质醇和 S-IgA。: 有面部疼痛的女性的 SFR 值显著较低，与对照组相比，面部疼痛组的龋齿易感性生物标志物与皮质醇水平之间的相关性不同。值得注意的是，较高的 SFR 值与患面部疼痛的可能性较低相关。: 在有面部疼痛的个体和无痛对照者之间观察到 SFR 值的差异，特别是在女性中，以及分析的唾液生物标志物之间明显不同的相互作用。因此，唾液动力学、应激反应和面部疼痛感知之间可能存在联系。
