Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.
Biosensors (Basel). 2019 May 1;9(2):61. doi: 10.3390/bios9020061.
Antibiotics are an important class of drugs destined for treatment of bacterial diseases. Misuses and overuses of antibiotics observed over the last decade have led to global problems of bacterial resistance against antibiotics (ABR). One of the crucial actions taken towards limiting the spread of antibiotics and controlling this dangerous phenomenon is the sensitive and accurate determination of antibiotics residues in body fluids, food products, and animals, as well as monitoring their presence in the environment. Immunosensors, a group of biosensors, can be considered an attractive tool because of their simplicity, rapid action, low-cost analysis, and especially, the unique selectivity arising from harnessing the antigen-antibody interaction that is the basis of immunosensor functioning. Herein, we present the recent achievements in the field of electrochemical immunosensors designed to determination of antibiotics.
抗生素是一类用于治疗细菌疾病的重要药物。在过去十年中,抗生素的滥用和过度使用导致了全球范围内的细菌对抗生素的耐药性问题。为了限制抗生素的传播并控制这一危险现象,采取的关键措施之一是在体液、食品和动物中敏感和准确地检测抗生素残留,并监测其在环境中的存在。免疫传感器作为生物传感器的一个分支,由于其简单、快速、低成本的分析方法,特别是利用抗原-抗体相互作用的独特选择性(这是免疫传感器工作的基础),可以被认为是一种有吸引力的工具。本文介绍了电化学免疫传感器在抗生素检测领域的最新研究进展。