Madej Maria, Knihnicki Paweł, Porada Radosław, Kochana Jolanta
Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.
Biosensors (Basel). 2025 Feb 11;15(2):101. doi: 10.3390/bios15020101.
Tetracyclines (TCs) are antibiotics used extensively in medicine, veterinary science, and animal husbandry. Their overuse and the widespread presence of their residues in the environment contribute to intensifying the phenomenon of antibiotic resistance (ABR). The efforts are being made to reduce the spread of antibiotics and control the phenomenon of ABR, and one of the key methods is monitoring the presence of antibiotic residues in the environment and food of animal origin. Herein, we provide the overview of the recent developments in electrochemical (bio)sensing of tetracyclines in different types of samples. The review presents a comprehensive view of such aspects of the practical (bio)sensor application as sample preparation, the reusability of (bio)sensors, and the possibility of determining antibiotics at levels required by regulations. Advances, existing challenges, and future trends in the development of novel (bio)electrochemical methods of tetracycline quantification were discussed.
四环素(TCs)是广泛应用于医学、兽医学和畜牧业的抗生素。它们的过度使用以及在环境中残留的广泛存在,加剧了抗生素耐药性(ABR)现象。人们正在努力减少抗生素的传播并控制ABR现象,其中一个关键方法是监测环境和动物源性食品中抗生素残留的存在情况。在此,我们概述了不同类型样品中四环素电化学(生物)传感的最新进展。该综述全面介绍了实用(生物)传感器应用的各个方面,如样品制备、(生物)传感器的可重复使用性以及按照法规要求的水平测定抗生素的可能性。讨论了新型四环素定量电化学(生物)方法发展中的进展、现有挑战和未来趋势。