对编码、巩固和检索阶段选择性增强记忆的神经生物学因素的综述。
A review of neurobiological factors underlying the selective enhancement of memory at encoding, consolidation, and retrieval.
机构信息
School of Psychology, University of Kent, Canterbury, UK; Department of Psychology, Royal Holloway, University of London, London, UK.
Institute of Behavioural Neuroscience, University College London, London, UK.
出版信息
Prog Neurobiol. 2019 Aug;179:101615. doi: 10.1016/j.pneurobio.2019.04.004. Epub 2019 May 2.
How is the strength of a memory determined? This review discusses three main factors that contribute to memory enhancement - 1) emotion, 2) targeted memory reactivation, and 3) neural reinstatement. Whilst the mechanisms through which memories become enhanced vary, this review demonstrates that activation of the basolateral amygdala and hippocampal formation are crucial for facilitating encoding, consolidation, and retrieval. Here we suggest methodological factors to consider in future studies, and discuss several unanswered questions that should be pursued in order to clarify selective memory enhancement.
记忆的强度是如何决定的？本文综述了三个主要因素对记忆增强的贡献：1）情绪，2）目标记忆再激活，3）神经再激活。虽然记忆增强的机制不同，但本综述表明，基底外侧杏仁核和海马结构的激活对于促进编码、巩固和检索至关重要。在这里，我们建议在未来的研究中考虑一些方法学因素，并讨论了几个尚未解决的问题，这些问题应该被进一步研究，以阐明选择性记忆增强的机制。
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