球腔菌属致脑脓肿，腐生菌变为病原体：病例报告及文献复习。

Cladosporium sphaerospermum causing brain abscess, a saprophyte turning pathogen: Case and review of published reports.

机构信息

Department of Medical Microbiology, Post graduate institute of medical education and research, Chandigarh, India.

出版信息

J Mycol Med. 2019 Jun;29(2):180-184. doi: 10.1016/j.mycmed.2019.04.005. Epub 2019 May 2.

DOI:10.1016/j.mycmed.2019.04.005

Abstract

Emergence of saprophytic fungi thriving in dead plant material and soil as opportunistic human pathogens is of great concern. Cladosporium species are environmental saprophytes reported to cause various superficial and invasive fungal infections worldwide. C. sphaerospermum, a predominantly indoor fungus has been reported from cases of meningitis, subcutaneous and pulmonary fungal infections in the past. Herein we report the first case of cerebral abscess due to C. sphaerospermum in an immunocompetent host who was successfully managed by combined medical and surgical therapy.

摘要

腐生真菌在死亡植物材料和土壤中大量繁殖，成为机会性人体病原体，这引起了极大的关注。枝孢属真菌是一种在环境中生存的腐生菌，被报道在全球范围内引起各种浅表和侵袭性真菌感染。过去曾有报道称，主要存在于室内的球形枝孢菌可引起脑膜炎、皮下和肺部真菌感染。在此，我们报告了首例免疫功能正常宿主的脑脓肿病例，该病例由球形枝孢菌引起，经联合药物和手术治疗后成功治愈。