Ortega Laura, Llorella Anna, Esquivel Juan Pablo, Sabaté Neus
1Instituto de Microelectrónica de Barcelona, IMB-CNM (CSIC), C/del Til·lers. Campus Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Barcelona Spain.
2Catalan Institution for Research and Advanced Studies (ICREA), Passeig Lluís Companys 23, 08010 Barcelona, Spain.
Microsyst Nanoeng. 2019 Jan 28;5:3. doi: 10.1038/s41378-018-0043-0. eCollection 2019.
A self-powered skin patch for the measurement of sweat conductivity is presented. The key component of the patch consists of a paper battery that is activated upon absorption of sweat. This body fluid acts as the battery electrolyte, the conductivity of which has a direct impact on the battery-generated output power and voltage. This particular behaviour enables the operation of a very simple and robust conductivity sensor in direct current mode without needing an external power source. The device presented in this paper takes advantage of this new measurement method to develop a sweat patch for screening cystic fibrosis that operates with an extremely simple electronic circuit that minimizes its cost and environmental impact. The patch provides an unambiguous digital result that can be read in an electrochromic display and yields 95% sensitivity and 100% specificity when tested with artificial eccrine perspiration samples.
本文介绍了一种用于测量汗液电导率的自供电皮肤贴片。该贴片的关键组件是一个纸电池，它在吸收汗液时被激活。这种体液充当电池电解质，其电导率直接影响电池产生的输出功率和电压。这种特殊行为使得无需外部电源就能在直流模式下运行一个非常简单且坚固的电导率传感器。本文介绍的设备利用这种新的测量方法开发了一种用于筛查囊性纤维化的汗液贴片，该贴片采用极其简单的电子电路运行，从而将成本和环境影响降至最低。该贴片提供明确的数字结果，可在电致变色显示器上读取，在用人工分泌的汗液样本进行测试时，灵敏度为95%，特异性为100%。
