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牙周炎与高脂血症双向关系的批判性评估

Critical Appraisal of Bidirectional Relationship between Periodontitis and Hyperlipidemia.

作者信息

Abraham Seba, Premnath Arya, Arunima P R, Kassim Reejamol Mohammed

机构信息

Department of Periodontology, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.

出版信息

J Int Soc Prev Community Dent. 2019 Mar-Apr;9(2):112-118. doi: 10.4103/jispcd.JISPCD_316_18. Epub 2019 Apr 12.

DOI:10.4103/jispcd.JISPCD_316_18
PMID:31058060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6489519/
Abstract

Periodontal disease and hyperlipidemia are both multifactorial disease with a high prevalence Worldwide. Cross-sectional and longitudinal prospective clinical studies show some evidence for a bidirectional relationship. Periodontitis and hyperlipidemia share some common risk factors and there exist a mechanistic link between both. Studies have found a positive response to periodontal therapy among hyperlipidemic patients, and statin use by hyperlipidemic patients has shown to influence the periodontal health. However, in spite of the rising prevalence of both diseases, many people remain unaware of their association with each other. Hence, this article summarizes the cyclic relationship between periodontal disease and hyperlipidemia.

摘要

牙周病和高脂血症都是多因素疾病,在全球范围内患病率很高。横断面和纵向前瞻性临床研究显示了二者双向关系的一些证据。牙周炎和高脂血症有一些共同的危险因素,并且二者之间存在机制上的联系。研究发现高脂血症患者对牙周治疗有积极反应,高脂血症患者使用他汀类药物已显示会影响牙周健康。然而,尽管这两种疾病的患病率都在上升,但许多人仍然没有意识到它们之间的关联。因此,本文总结了牙周病和高脂血症之间的循环关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a000/6489519/b15d579ee5d0/JISPCD-9-112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a000/6489519/b15d579ee5d0/JISPCD-9-112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a000/6489519/b15d579ee5d0/JISPCD-9-112-g001.jpg

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本文引用的文献

1
Periodontal Disease and Cardiovascular Disease.牙周病与心血管疾病
J Periodontol. 1996 Oct;67 Suppl 10S:1123-1137. doi: 10.1902/jop.1996.67.10s.1123.
2
The effect of statins on periodontal treatment-a systematic review with meta-analyses and meta-regression.他汀类药物对牙周治疗效果的系统评价:荟萃分析和荟萃回归。
Clin Oral Investig. 2018 Mar;22(2):671-687. doi: 10.1007/s00784-018-2354-9. Epub 2018 Feb 2.
3
Association between periodontitis and blood lipid levels in a Korean population.牙周炎与韩国人群血脂水平的关系。
牙周炎与高血脂人群全因死亡率及死因特异性死亡率的相关性。
BMC Oral Health. 2024 Oct 19;24(1):1246. doi: 10.1186/s12903-024-05055-2.
4
Association between periodontal disease and hypertriglyceridemia: Propensity score matching analysis using the 7th Korea National Health and Nutrition Examination Survey.牙周病与高甘油三酯血症的相关性:基于第 7 次韩国国家健康和营养检查调查的倾向评分匹配分析。
Medicine (Baltimore). 2023 Dec 22;102(51):e36502. doi: 10.1097/MD.0000000000036502.
5
Periodontitis is associated with stroke.牙周炎与中风有关。
J Transl Med. 2023 Oct 6;21(1):697. doi: 10.1186/s12967-023-04545-1.
6
Influencing factors associated with oral health among older hospitalized patients with ischemic stroke: A cross-sectional survey.老年缺血性脑卒中住院患者口腔健康的相关影响因素:一项横断面调查。
Int J Nurs Sci. 2023 Jun 24;10(3):302-308. doi: 10.1016/j.ijnss.2023.06.011. eCollection 2023 Jul.
7
Periodontal Disease in Young Adults as a Risk Factor for Subclinical Atherosclerosis: A Clinical, Biochemical and Immunological Study.年轻成年人牙周病作为亚临床动脉粥样硬化的危险因素:一项临床、生化和免疫学研究。
J Clin Med. 2023 Mar 12;12(6):2197. doi: 10.3390/jcm12062197.
8
Type 1 diabetes, periodontal health, and a familial history of hyperlipidaemia is associated with oral microbiota in children: a cross-sectional study.1 型糖尿病、牙周健康和家族性高脂血症与儿童口腔微生物群有关:一项横断面研究。
BMC Oral Health. 2023 Jan 11;23(1):15. doi: 10.1186/s12903-022-02625-0.
9
Periodontal Therapy in Bariatric Surgery Patients with Periodontitis: Randomized Control Clinical Trial.肥胖症手术患者牙周炎的牙周治疗:随机对照临床试验。
J Clin Med. 2022 Nov 19;11(22):6837. doi: 10.3390/jcm11226837.
10
Periodontal and systemic health of morbidly obese patients eligible for bariatric surgery: a cross-sectional study.肥胖症患者行减重手术的牙周及全身健康状况:一项横断面研究。
BMC Oral Health. 2022 May 13;22(1):174. doi: 10.1186/s12903-022-02207-0.
J Periodontol. 2018 Jan;89(1):28-35. doi: 10.1902/jop.2017.170111.
4
Serum lipid levels in patients with periodontal disease: A meta-analysis and meta-regression.牙周病患者的血清脂质水平:荟萃分析和荟萃回归。
J Clin Periodontol. 2017 Dec;44(12):1192-1207. doi: 10.1111/jcpe.12792. Epub 2017 Nov 17.
5
Triglyceride to high density lipoprotein cholesterol ratio and its association with periodontal disease in Korean adults: findings based on the 2012-2014 Korean national health and nutrition examination survey.甘油三酯与高密度脂蛋白胆固醇比值与韩国成年人牙周病的关系:基于 2012-2014 年韩国国家健康和营养检查调查的结果。
Clin Oral Investig. 2018 Jan;22(1):515-522. doi: 10.1007/s00784-017-2140-0. Epub 2017 Jun 6.
6
Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function.香烟烟雾提取物可抵消高层流对内皮功能的动脉粥样硬化保护作用。
Redox Biol. 2017 Aug;12:776-786. doi: 10.1016/j.redox.2017.04.008. Epub 2017 Apr 7.
7
Clinical efficacy of subgingivally delivered simvastatin gel in chronic periodontitis patients.龈下给药辛伐他汀凝胶对慢性牙周炎患者的临床疗效
J Indian Soc Periodontol. 2016 Jul-Aug;20(4):409-416. doi: 10.4103/0972-124X.194270.
8
The Effect of Locally Delivered Statins on Treating Periodontal Intrabony Defects: A Systematic Review and Meta-Analysis.局部给予他汀类药物治疗牙周内骨缺损的效果:系统评价和荟萃分析。
J Periodontol. 2017 Apr;88(4):357-367. doi: 10.1902/jop.2016.160384. Epub 2016 Oct 21.
9
The influence of oral administration of rosuvastatin on calvarial bone healing in rats.口服瑞舒伐他汀对大鼠颅骨愈合的影响。
J Craniomaxillofac Surg. 2016 Sep;44(9):1327-32. doi: 10.1016/j.jcms.2016.04.021. Epub 2016 Apr 22.
10
Association Between High Serum Total Cholesterol and Periodontitis: National Health and Nutrition Examination Survey 2011 to 2012 Study of American Adults.
J Periodontol. 2016 Nov;87(11):1286-1294. doi: 10.1902/jop.2016.150648. Epub 2016 Jul 23.