Xu Qian, Wang Wenting, Li Yiwen, Cui Jing, Zhu Mengmeng, Liu Yanfei, Liu Yue
National Clinical Research Center for TCM Cardiology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 100091, Beijing, China.
The Second Department of Geriatrics, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 100091, Beijing, China.
NPJ Biofilms Microbiomes. 2025 Jan 10;11(1):11. doi: 10.1038/s41522-025-00646-5.
The oral-gut microbiota axis plays a crucial role in cardiometabolic health. This review explores the interactions between these microbiomes through enteric, hematogenous, and immune pathways, resulting in disruptions in microbial balance and metabolic processes. These disruptions contribute to systemic inflammation, metabolic disorders, and endothelial dysfunction, which are closely associated with cardiometabolic diseases. Understanding these interactions provides insights for innovative therapeutic strategies to prevent and manage cardiometabolic diseases.
口腔-肠道微生物群轴在心脏代谢健康中起着至关重要的作用。本综述探讨了这些微生物群通过肠道、血行和免疫途径之间的相互作用，导致微生物平衡和代谢过程的破坏。这些破坏会导致全身炎症、代谢紊乱和内皮功能障碍，而这些都与心脏代谢疾病密切相关。了解这些相互作用为预防和管理心脏代谢疾病的创新治疗策略提供了见解。
