Griez E J, Lousberg H, van den Hout M A, van der Molen G M
Psychiatry Res. 1987 Feb;20(2):87-95. doi: 10.1016/0165-1781(87)90001-1.
The immediate effects of a single inhalation of a 35% CO2 mixture in oxygen were examined in 12 patients with panic disorders and 11 normal control subjects. Compared to a placebo air inhalation, the CO2 inhalation provoked short-lived autonomic panic symptoms in both patients and normals; it also elicited high subjective anxiety in patients with panic disorders. The latter rated the overall CO2-induced state as very similar to a real-life panic attack.
对12名惊恐障碍患者和11名正常对照者进行了研究，观察单次吸入含35%二氧化碳的氧气混合物后的即时效应。与吸入安慰剂空气相比，吸入二氧化碳在患者和正常人中均引发了短暂的自主神经惊恐症状；它还在惊恐障碍患者中引发了高度的主观焦虑。后者将二氧化碳诱发的总体状态评定为与现实生活中的惊恐发作非常相似。
