在海藻酸钠水凝胶微球中包埋的微胶囊的存活。
survival of microencapsulated in zein-coated alginate hydrogel microbeads.
机构信息
a State Key Laboratory of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu , China.
b International Joint Laboratory on Food Safety , Jiangnan University , Wuxi , Jiangsu , China.
出版信息
J Microencapsul. 2019 Mar;36(2):192-203. doi: 10.1080/02652048.2019.1618403. Epub 2019 May 28.
The susceptibility in gastrointestinal conditions and storage stability limit its use as potential probiotics. The current study was design to encapsulate using sodium alginate (SA, 1.4% w/v) and different concentration of zein as coating material, that is, (1% w/v), (3% w/v), (5% w/v), (7% w/v), (9% w/v). The resultant microbeads were further investigated for encapsulation efficiency, survival in gastrointestinal conditions, release profile in intestinal fluid, storage stability and morphological characteristics. The highest encapsulation efficiency (94.56%) and viable count (>10 log CFU/g) was observed in (7% w/v). Viable cell count of . was >10 log CFU/g in all the zein-coated microbeads as compare to free cells (10 log CFU/g) and SA (10 log CFU/g) at 4 °C after 32 days of storage. Therefore, encapsulated in zein-coated alginate microbeads present improved survival during gastric transit and storage.
在胃肠道条件下的易感性和储存稳定性限制了其作为潜在益生菌的使用。本研究旨在使用海藻酸钠（SA，1.4%w/v）和不同浓度的玉米醇溶蛋白作为包埋材料来包埋，即（1%w/v）、（3%w/v）、（5%w/v）、（7%w/v）、（9%w/v）。进一步研究了所得微球的包埋效率、在胃肠道条件下的存活情况、在肠液中的释放特性、储存稳定性和形态特征。在（7%w/v）中观察到最高的包埋效率（94.56%）和存活计数（>10logCFU/g）。与游离细胞（10logCFU/g）和 SA（10logCFU/g）相比，在 4°C 下储存 32 天后，所有用玉米醇溶蛋白包被的微球中的活菌计数（>10logCFU/g）均为>10logCFU/g。因此，包埋在玉米醇溶蛋白包被的海藻酸钠微球中，在胃转运和储存过程中的存活能力得到了提高。
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