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Q 热的发现及其病因。

The Discovery of Q Fever and Its Cause.

机构信息

Emeritus Professor of Medicine, University of Washington, Seattle Washington.

出版信息

Am J Med Sci. 2019 Jul;358(1):3-10. doi: 10.1016/j.amjms.2019.04.006. Epub 2019 Apr 12.

Abstract

An outbreak of a febrile illness among workers in a slaughterhouse in Brisbane, Australia led E.H. Derrick to discover a new infection, which he labeled Q fever. Almost simultaneously, investigators in Montana discovered a new organism in ticks that caused fever in guinea pigs. Eventually, investigators found that the Q fever and tick microbes were identical. Outbreaks of Q fever occurred in laboratories, and epidemics of it affected both Axis and Allied troops in Europe during World War II, but it was only afterwards that an explanation emerged about what the major reservoir of the organism was and how infection was most commonly transmitted to animals and humans.

摘要

澳大利亚布里斯班一家屠宰场的工人中爆发了一种发热疾病,这促使 E.H.德里克发现了一种新的感染,他将其命名为 Q 热。几乎与此同时,蒙大拿州的研究人员在蜱虫中发现了一种新的微生物,这种微生物会导致豚鼠发热。最终,研究人员发现 Q 热和蜱虫微生物是相同的。Q 热爆发发生在实验室,第二次世界大战期间,这种疾病在欧洲的轴心国和盟国军队中也流行起来,但直到后来,人们才对该微生物的主要宿主以及感染动物和人类的最常见传播途径有了一个解释。

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