Waziri R, Mott J
Eur Arch Psychiatry Neurol Sci. 1987;236(4):251-5. doi: 10.1007/BF00383858.
Thirteen brain dysfunctional patients with psychosis were compared to 11 brain dysfunctional patients without psychosis by EEG, CT scan and neuropsychological test abnormalities, and abnormalities in serine metabolism. None of the tests of conventional measures of brain pathology and pathophysiology significantly differentiated between the psychotic and nonpsychotic patients; only the last measure which has previously been shown to be a biochemical vulnerability factor for psychosis, was significantly different in the two groups. This study suggests that the brain pathology and pathophysiology per se are not significant factors that make such patients psychotic, but these patients are vulnerable to psychosis because of a biochemical abnormality.
通过脑电图、CT扫描、神经心理学测试异常以及丝氨酸代谢异常，对13名患有精神病的脑功能障碍患者与11名无精神病的脑功能障碍患者进行了比较。传统的脑病理学和病理生理学测量方法均未在精神病患者和非精神病患者之间显示出显著差异；只有先前已被证明是精神病生化易感性因素的最后一项测量，在两组中存在显著差异。这项研究表明，脑病理学和病理生理学本身并不是使这些患者患精神病的重要因素，但这些患者由于生化异常而易患精神病。
