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2013 - 2017年北京市通州区手足口病流行病学研究

Epidemiological study on hand, foot and mouth disease in Tongzhou District, Beijing, 2013-2017.

作者信息

Liu Xiao-Feng, Sun Xiu-Mei, Sun Xiao-Wei, Yang Yu-Qing, Huang Cong-Hui, Wen Han

机构信息

1 Administrative Office, Beijing Centre for Disease Prevention and Control, Dongcheng District, Beijing, China.

2 Business Management Office, Tongzhou District Centre for Disease Prevention and Control, Tongzhou District, Beijing, China.

出版信息

J Int Med Res. 2019 Jun;47(6):2615-2625. doi: 10.1177/0300060519841974. Epub 2019 May 17.

DOI:10.1177/0300060519841974
PMID:31099288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6567722/
Abstract

OBJECTIVE

To study the epidemiological characteristics of hand, foot and mouth disease (HFMD) in Tongzhou District, Beijing between 2013 and 2017.

METHODS

Data on HFMD infections from 1 January 2013 to 31 December 2017 were collected from the Notifiable Infectious Diseases Reporting Information System and analysed. Serotyping of enteroviruses from samples from patients with HFMD was undertaken using reverse transcription-polymerase chain reaction.

RESULTS

A total of 15 341 patients with HFMD were reported and 32 patients (0.2%) were classified as having severe HFMD. The annual mean incidence rate of HFMD was 219.3/100 000 of the general population. The incidence and case-severity rates of HFMD generally decreased between 2013 and 2017. In the floating migrant population, the incidence and cases-severity rates of HFMD were significantly higher than in the local population. The peak incidence and severity-case rates were at 2 years of age and > 90% of patients were ≤5 years. Enterovirus A71 and Coxsackievirus A16 were the predominant pathogens in 2013-2017.

CONCLUSIONS

During the 5-year period 2013-2017, the incidence rate and case-severity rate of HFMD generally decreased in Tongzhou District, Beijing. The floating migrant population and children ≤5 years of age were at the highest risk of HFMD.

摘要

目的

研究2013年至2017年北京市通州区手足口病（HFMD）的流行病学特征。

方法

从法定传染病报告信息系统收集2013年1月1日至2017年12月31日期间手足口病感染的数据并进行分析。采用逆转录-聚合酶链反应对手足口病患者样本中的肠道病毒进行血清分型。

结果

共报告15341例手足口病患者，32例（0.2%）被归类为重症手足口病。手足口病的年平均发病率为每10万总人口219.3例。2013年至2017年期间，手足口病的发病率和病例严重程度总体呈下降趋势。在流动人口中，手足口病的发病率和病例严重程度显著高于本地人口。发病高峰年龄为2岁，超过90%的患者年龄≤5岁。肠道病毒A71和柯萨奇病毒A16是2013年至2017年的主要病原体。

结论

在2013年至2017年的5年期间，北京市通州区手足口病的发病率和病例严重程度总体呈下降趋势。流动人口和≤5岁儿童手足口病感染风险最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/b0dff09186af/10.1177_0300060519841974-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/e699d52707fa/10.1177_0300060519841974-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/8b366c7eddd7/10.1177_0300060519841974-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/a5d6380a0bd5/10.1177_0300060519841974-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/6f6920e0c769/10.1177_0300060519841974-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/8f1d8bc70e27/10.1177_0300060519841974-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/23e04d6d27b1/10.1177_0300060519841974-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/b0dff09186af/10.1177_0300060519841974-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/e699d52707fa/10.1177_0300060519841974-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/8b366c7eddd7/10.1177_0300060519841974-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/a5d6380a0bd5/10.1177_0300060519841974-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/6f6920e0c769/10.1177_0300060519841974-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/8f1d8bc70e27/10.1177_0300060519841974-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/23e04d6d27b1/10.1177_0300060519841974-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55c8/6567722/b0dff09186af/10.1177_0300060519841974-fig7.jpg

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