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英国中年男性的A型行为与缺血性心脏病

Type A behaviour and ischaemic heart disease in middle aged British men.

作者信息

Johnston D W, Cook D G, Shaper A G

出版信息

Br Med J (Clin Res Ed). 1987 Jul 11;295(6590):86-9. doi: 10.1136/bmj.295.6590.86.

Abstract

The Bortner questionnaire, which measures aspects of type A (coronary prone) behaviour was completed by 5936 men aged 40-59 selected at random from one general practice in each of 19 British towns. The presence of ischaemic heart disease was determined at initial examination and the men were followed up for an average of 6.2 years for morbidity and mortality from myocardial infarction and for sudden cardiac death. Non-manual workers had significantly higher scores (more type A) than manual workers and the score decreased (less type A) with increasing age. After adjustment for social class and age men with higher scores had higher prevalences of ischaemic heart disease less marked for electrocardiographic evidence and more marked for response to a chest pain questionnaire (angina or possible myocardial infarction). A man's recall of a doctor's diagnosis of ischaemic heart disease, however, did not relate to his Bortner score. There was no significant relation between the Bortner score and the attack rate or incidence of major ischaemic heart disease events. In this study type A behaviour, as measured by the Bortner questionnaire, did not predict major ischaemic heart disease events in British middle aged men.

摘要

博特纳问卷用于测量A型(易患冠心病)行为的各个方面,该问卷由从英国19个城镇的每个城镇的一家普通诊所中随机抽取的5936名年龄在40至59岁之间的男性填写。在初次检查时确定是否存在缺血性心脏病,并对这些男性进行平均6.2年的随访,以了解心肌梗死的发病率和死亡率以及心源性猝死情况。非体力劳动者的得分(A型行为更多)显著高于体力劳动者,且得分随着年龄增长而降低(A型行为减少)。在对社会阶层和年龄进行调整后,得分较高的男性缺血性心脏病的患病率更高,这在心电图证据方面不太明显,而在胸痛问卷(心绞痛或可能的心肌梗死)的反应方面更为明显。然而,男性对医生诊断缺血性心脏病的回忆与他的博特纳得分无关。博特纳得分与主要缺血性心脏病事件的发作率或发病率之间没有显著关系。在这项研究中,通过博特纳问卷测量的A型行为并不能预测英国中年男性的主要缺血性心脏病事件。

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