Vlaanderen W, Treffers P E
Br Med J (Clin Res Ed). 1987 Jul 11;295(6590):92-3. doi: 10.1136/bmj.295.6590.92.
The outcome of subsequent pregnancies was studied in 24 women with a history of three or more consecutive spontaneous abortions in the first trimester. Twenty one of the women agreed to forgo active treatment during the study period and three received progestogens or surgical intervention. As the outcome of their first pregnancy after recurrent abortion 18 of the 24 women delivered a liveborn infant after 28 weeks or more. Of all 49 pregnancies in the untreated group during the study, 10 ended in abortion. Only one woman in the study failed to achieve a live birth. Except in exceptional cases encouraging women with recurrent abortion to keep trying for a successful outcome is just as effective as currently recommended treatments.
对24名有孕早期连续三次或更多次自然流产史的女性的后续妊娠结局进行了研究。其中21名女性同意在研究期间不进行积极治疗,3名接受了孕激素治疗或手术干预。在反复流产后的首次妊娠中,24名女性中有18名在孕28周或更晚时分娩出活产婴儿。在研究期间,未治疗组的所有49次妊娠中,有10次以流产告终。研究中只有一名女性未能实现活产。除特殊情况外,鼓励反复流产的女性继续尝试以获得成功结局与目前推荐的治疗方法同样有效。