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本文引用的文献

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Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.全球、区域和国家按年龄、性别和死因分类的死亡率，195 个国家和地区，1980-2017 年：2017 年全球疾病负担研究的系统分析。
Lancet. 2018 Nov 10;392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7. Epub 2018 Nov 8.
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Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults.Pfs25H-EPA/Alhydrogel 作为一种针对恶性疟原虫的传播阻断疫苗的安全性和免疫原性：在健康马里成年人中进行的随机、双盲、对照、剂量递增研究。
Lancet Infect Dis. 2018 Sep;18(9):969-982. doi: 10.1016/S1473-3099(18)30344-X. Epub 2018 Jul 27.
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3. How comprehensive can we be in the economic assessment of vaccines?3. 在疫苗的经济评估中，我们能做到多全面？
J Mark Access Health Policy. 2017 Aug 31;5(1):1336044. doi: 10.1080/20016689.2017.1336044. eCollection 2017.
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Awareness, perceptions and intent to comply with the prospective malaria vaccine in parts of South Eastern Nigeria.尼日利亚东南部地区对未来疟疾疫苗的认知、看法和接种意愿。
Malar J. 2018 May 2;17(1):187. doi: 10.1186/s12936-018-2335-0.
5
Acceptability of a herd immunity-focused, transmission-blocking malaria vaccine in malaria-endemic communities in the Peruvian Amazon: an exploratory study.在秘鲁亚马逊地区的疟疾流行社区中，针对群体免疫和阻断传播的疟疾疫苗的可接受性：一项探索性研究。
Malar J. 2018 Apr 27;17(1):179. doi: 10.1186/s12936-018-2328-z.
6
Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium.疟疾疫苗研发进展：2017年疟疾疫苗研讨会报告
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PLoS One. 2016 Oct 17;11(10):e0163144. doi: 10.1371/journal.pone.0163144. eCollection 2016.
8
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Assessment of parental perception of malaria vaccine in Tanzania.坦桑尼亚父母对疟疾疫苗认知的评估。
Malar J. 2015 Sep 17;14:355. doi: 10.1186/s12936-015-0889-7.

疟疾传播阻断疫苗：是时候讨论疫苗引入了。

Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction.

机构信息

Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA.

GlaxoSmithKline, Via Fiorentina 1, 53100 Siena, Italy.

出版信息

Trends Parasitol. 2019 Jul;35(7):483-486. doi: 10.1016/j.pt.2019.04.008. Epub 2019 May 29.

DOI:10.1016/j.pt.2019.04.008
PMID:31153722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11127249/
Abstract

Malaria kills more than 600 000 people yearly, mainly children, and eradication is a global priority. Malaria transmission-blocking vaccines are advancing in clinical trials, and strategies for their introduction must be prioritized among stakeholders and the vulnerable populations exposed to the disease.

摘要

疟疾每年导致超过 60 万人死亡，其中主要是儿童，因此消除疟疾是全球的重点工作。阻断疟疾传播的疫苗正在临床试验中取得进展，利益相关者和易感染疟疾的脆弱人群必须优先考虑引入这些疫苗的策略。