• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

抗铜绿假单胞菌血清型菌株单克隆抗体的制备。

Production of monoclonal antibodies against serotype strains of Pseudomonas aeruginosa.

作者信息

Lam J S, MacDonald L A, Lam M Y

机构信息

Department of Microbiology, College of Biological Science, University of Guelph, Ontario, Canada.

出版信息

Infect Immun. 1987 Nov;55(11):2854-6. doi: 10.1128/iai.55.11.2854-2856.1987.

DOI:10.1128/iai.55.11.2854-2856.1987
PMID:3117697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC259990/
Abstract

A panel of 22 monoclonal antibodies against 8 of the 17 International Antigenic Typing Scheme (IATS) serotypes of Pseudomonas aeruginosa was produced. The antibodies were characterized for cross-reactivities, isotypes, titers, and epitope specificities. The results complemented those of our previous study and marked the completion of a set of monoclonal antibodies for serotyping P. aeruginosa.

摘要

制备了一组针对铜绿假单胞菌17种国际抗原分型方案（IATS）血清型中8种血清型的22种单克隆抗体。对这些抗体的交叉反应性、免疫球蛋白类型、效价和表位特异性进行了表征。这些结果补充了我们之前研究的结果，并标志着用于铜绿假单胞菌血清分型的一组单克隆抗体的完成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e7/259990/011bfe5967aa/iai00095-0326-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e7/259990/011bfe5967aa/iai00095-0326-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e7/259990/011bfe5967aa/iai00095-0326-a.jpg

相似文献

1
Production of monoclonal antibodies against serotype strains of Pseudomonas aeruginosa.抗铜绿假单胞菌血清型菌株单克隆抗体的制备。
Infect Immun. 1987 Nov;55(11):2854-6. doi: 10.1128/iai.55.11.2854-2856.1987.
2
Production and characterization of monoclonal antibodies against serotype strains of Pseudomonas aeruginosa.抗铜绿假单胞菌血清型菌株单克隆抗体的制备与鉴定
Infect Immun. 1987 May;55(5):1051-7. doi: 10.1128/iai.55.5.1051-1057.1987.
3
Preclinical in vitro and in vivo characterization of the fully human monoclonal IgM antibody KBPA101 specific for Pseudomonas aeruginosa serotype IATS-O11.针对铜绿假单胞菌血清型 IATS-O11 的全人源单克隆 IgM 抗体 KBPA101 的临床前体外和体内特性研究。
Antimicrob Agents Chemother. 2010 Jun;54(6):2338-44. doi: 10.1128/AAC.01142-09. Epub 2010 Mar 22.
4
Characterisation of mouse monoclonal antibodies produced by immunisation with a single serotype component of a polyvalent Pseudomonas aeruginosa vaccine.
J Med Microbiol. 1986 Feb;21(1):87-90. doi: 10.1099/00222615-21-1-87.
5
Subdivision of O serotypes of Pseudomonas aeruginosa with monoclonal antibodies.用单克隆抗体对铜绿假单胞菌O血清型进行细分
J Clin Microbiol. 1988 Sep;26(9):1779-82. doi: 10.1128/jcm.26.9.1779-1782.1988.
6
Serologic and molecular characterization of Pseudomonas aeruginosa Jordanian clinical isolates compared with the strains of International Antigenic Typing Scheme.与国际抗原分型方案菌株相比，约旦铜绿假单胞菌临床分离株的血清学和分子特征
Diagn Microbiol Infect Dis. 2007 Aug;58(4):393-8. doi: 10.1016/j.diagmicrobio.2007.03.005. Epub 2007 May 16.
7
Comparison of polyclonal rabbit antisera with monoclonal antibodies for serological typing of Pseudomonas aeruginosa.用于铜绿假单胞菌血清学分型的多克隆兔抗血清与单克隆抗体的比较。
J Clin Microbiol. 1988 Apr;26(4):768-9. doi: 10.1128/jcm.26.4.768-769.1988.
8
Variable cross-reactivity of Pseudomonas aeruginosa lipopolysaccharide-code-specific monoclonal antibodies and its possible relationship with serotype.
J Gen Microbiol. 1992 Feb;138(2):289-96. doi: 10.1099/00221287-138-2-289.
9
Surveillance of gram-negative bacteria for Pseudomonas aeruginosa lipoprotein I using a monoclonal antibody.使用单克隆抗体对铜绿假单胞菌脂蛋白I进行革兰氏阴性菌监测。
Hybridoma. 1993 Jun;12(3):327-32. doi: 10.1089/hyb.1993.12.327.
10
Monoclonal antibodies against Pseudomonas aeruginosa outer membrane antigens: isolation and characterization.抗铜绿假单胞菌外膜抗原的单克隆抗体：分离与鉴定
Infect Immun. 1982 Jul;37(1):166-71. doi: 10.1128/iai.37.1.166-171.1982.

引用本文的文献

1
Conserved-residue mutations in Wzy affect O-antigen polymerization and Wzz-mediated chain-length regulation in Pseudomonas aeruginosa PAO1.Wzy中的保守残基突变影响铜绿假单胞菌PAO1中的O抗原聚合和Wzz介导的链长调节。
Sci Rep. 2013 Dec 6;3:3441. doi: 10.1038/srep03441.
2
Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post-transcriptionally regulated.多种铜绿假单胞菌生物膜基质胞外多糖的合成是转录后调控的。
Environ Microbiol. 2012 Aug;14(8):1995-2005. doi: 10.1111/j.1462-2920.2012.02753.x. Epub 2012 Apr 19.
3
Epidemiological studies of nosocomial infections with Pseudomonas aeruginosa using a DNA probe.

本文引用的文献

1
Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains.从光滑型和粗糙型铜绿假单胞菌及鼠伤寒沙门氏菌菌株中分离细菌脂多糖的方法。
J Bacteriol. 1983 Aug;155(2):831-8. doi: 10.1128/jb.155.2.831-838.1983.
2
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.“蛋白质免疫印迹法”：蛋白质从十二烷基硫酸钠 - 聚丙烯酰胺凝胶电泳转移至未修饰的硝酸纤维素膜上，并用抗体和放射性碘化蛋白A进行放射自显影检测。
Anal Biochem. 1981 Apr;112(2):195-203. doi: 10.1016/0003-2697(81)90281-5.
3
使用DNA探针进行铜绿假单胞菌医院感染的流行病学研究。
Can J Infect Dis. 1992 Nov;3(6):299-306. doi: 10.1155/1992/809648.
4
Genetic and Functional Diversity of Pseudomonas aeruginosa Lipopolysaccharide.铜绿假单胞菌脂多糖的遗传与功能多样性
Front Microbiol. 2011 Jun 1;2:118. doi: 10.3389/fmicb.2011.00118. eCollection 2011.
5
Coexistence of two distinct versions of O-antigen polymerase, Wzy-alpha and Wzy-beta, in Pseudomonas aeruginosa serogroup O2 and their contributions to cell surface diversity.铜绿假单胞菌O2血清群中两种不同版本的O抗原聚合酶Wzy-α和Wzy-β的共存及其对细胞表面多样性的贡献。
J Bacteriol. 2007 Jun;189(11):4141-52. doi: 10.1128/JB.00237-07. Epub 2007 Mar 23.
6
Genetics of O-antigen biosynthesis in Pseudomonas aeruginosa.铜绿假单胞菌O抗原生物合成的遗传学
Microbiol Mol Biol Rev. 1999 Sep;63(3):523-53. doi: 10.1128/MMBR.63.3.523-553.1999.
7
Occurrence of a common lipopolysaccharide antigen in standard and clinical strains of Pseudomonas aeruginosa.铜绿假单胞菌标准菌株和临床菌株中共同脂多糖抗原的存在情况。
J Clin Microbiol. 1989 May;27(5):962-7. doi: 10.1128/jcm.27.5.962-967.1989.
8
Isolation and characterization of monoclonal antibodies against alkaline phosphatase of Pseudomonas aeruginosa.铜绿假单胞菌碱性磷酸酶单克隆抗体的分离与鉴定
J Clin Microbiol. 1989 May;27(5):1115-8. doi: 10.1128/jcm.27.5.1115-1118.1989.
9
Monoclonal antibodies as probes to examine serotype-specific and cross-reactive epitopes of lipopolysaccharides from serotypes O2, O5, and O16 of Pseudomonas aeruginosa.单克隆抗体作为探针，用于检测铜绿假单胞菌O2、O5和O16血清型脂多糖的血清型特异性和交叉反应性表位。
J Bacteriol. 1992 Apr;174(7):2178-84. doi: 10.1128/jb.174.7.2178-2184.1992.
Characterization of mouse monoclonal antibodies directed against Pseudomonas aeruginosa lipopolysaccharides.
针对铜绿假单胞菌脂多糖的小鼠单克隆抗体的特性分析。
Antibiot Chemother (1971). 1985;36:134-46. doi: 10.1159/000410478.
4
Immunochemical and biochemical analysis of the polyvalent Pseudomonas aeruginosa vaccine PEV.多价铜绿假单胞菌疫苗PEV的免疫化学和生化分析。
Infect Immun. 1986 Feb;51(2):675-86. doi: 10.1128/iai.51.2.675-686.1986.
5
Production and characterization of monoclonal antibodies against serotype strains of Pseudomonas aeruginosa.抗铜绿假单胞菌血清型菌株单克隆抗体的制备与鉴定
Infect Immun. 1987 May;55(5):1051-7. doi: 10.1128/iai.55.5.1051-1057.1987.
6
Continuous cultures of fused cells secreting antibody of predefined specificity.分泌预定义特异性抗体的融合细胞的连续培养物。
Nature. 1975 Aug 7;256(5517):495-7. doi: 10.1038/256495a0.
7
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.蛋白质从聚丙烯酰胺凝胶到硝酸纤维素膜的电泳转移：方法及一些应用
Proc Natl Acad Sci U S A. 1979 Sep;76(9):4350-4. doi: 10.1073/pnas.76.9.4350.
8
Outer membrane of Pseudomonas aeruginosa: heat- 2-mercaptoethanol-modifiable proteins.铜绿假单胞菌外膜：热 2 - 巯基乙醇可修饰蛋白。
J Bacteriol. 1979 Dec;140(3):902-10. doi: 10.1128/jb.140.3.902-910.1979.