Haque Mainul, Rahman Nor Azlina A, McKimm Judy, Kibria Golam Mohammad, Azim Majumder Md Anwarul, Haque Seraj Zohurul, Islam Md Zakirul, Binti Abdullah Shahidah Leong, Daher Aqil Mohammad, Zulkifli Zainal, Rahman Sayeeda, Kabir Russell, Lutfi Siti Nur Najihah Binti, Aishah Binti Othman Nur Syamirah
Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, 57000, Malaysia.
Department of Physical Rehabilitation Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan, 25200, Malaysia.
Infect Drug Resist. 2019 May 17;12:1333-1351. doi: 10.2147/IDR.S203364. eCollection 2019.
Self-medication of drugs to alleviate symptoms is a common global behavior, helping relieve burdens on health services, but many drugs eg, antibiotics are prescription-only. Self-medication of antibiotics (SMA) is an irrational use of drugs, contributing to microbial resistance increasing health care costs and higher mortality and morbidity. This study aimed to assess SMA among university students. This was a cross-sectional study conducted among medical and non-medical students of the National Defence University of Malaysia. A validated instrument was used to gather data. Ethics approval was obtained. Random and universal sampling was adopted, and SPSS 21 was used for data analysis. A total of 649 students participated in the study: 48.5% male and 51.5% female, 39.3% reported self-medicating with antibiotics. Penicillin, doxycycline, clarithromycin were the antibiotics most used with the majority reporting no adverse drug reactions. Cost savings and convenience were the principal reasons for SMA which were mainly obtained from local retail pharmacies. Despite medical students (particularly the more senior) having better knowledge of antibiotic use than non-medical students, 89% of all research participants responded that practicing SMA was a good/acceptable practice. SMA is common amongst Malaysian students and, despite understanding why SMA is unwise, even medical students self-medicate.
自行用药缓解症状是一种常见的全球行为，有助于减轻医疗服务负担，但许多药物，如抗生素，是凭处方购买的。自行服用抗生素（SMA）是一种不合理的用药行为，会导致微生物耐药性增加，提高医疗成本以及增加死亡率和发病率。本研究旨在评估大学生中的自行服用抗生素情况。这是一项在马来西亚国防大学的医学和非医学专业学生中开展的横断面研究。使用经过验证的工具收集数据。获得了伦理批准。采用随机和整群抽样，并使用SPSS 21进行数据分析。共有649名学生参与了该研究：48.5%为男性，51.5%为女性，39.3%的学生报告曾自行服用抗生素。青霉素、强力霉素、克拉霉素是最常使用的抗生素，大多数人报告没有药物不良反应。节省费用和方便是自行服用抗生素的主要原因，这些药物主要从当地零售药店获得。尽管医学生（尤其是高年级学生）比非医学生对抗生素使用有更好的了解，但所有研究参与者中有89%的人表示自行服用抗生素是一种良好/可接受的做法。自行服用抗生素在马来西亚学生中很常见，而且，尽管他们明白自行服用抗生素不明智，但即使是医学生也会自行用药。
