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脉络膜神经鞘瘤伴新生血管性青光眼:两例报告

Choroidal schwannoma presenting with neovascular glaucoma: A report of two cases.

作者信息

Jajapuram Sai Divya, Mishra Dilip K, Kaliki Swathi

机构信息

The Operation Eyesight Universal Institute for Eye Cancer, Hyderabad, Telangana, India.

Ophthalmic Pathology Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India.

出版信息

Oman J Ophthalmol. 2019 May-Aug;12(2):125-128. doi: 10.4103/ojo.OJO_123_2018.

DOI:10.4103/ojo.OJO_123_2018
PMID:31198301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6561046/
Abstract

Schwannoma is a rare benign tumor, which is more commonly found elsewhere in the body along myelin-producing peripheral nerves and is rarely reported within the eye. In this report, we describe two adult patients presenting with a choroidal mass lesion and neovascular glaucoma who underwent enucleation with clinical differential diagnoses of choroidal melanoma and choroidal hemangioma. Histopathology confirmed the diagnosis of choroidal schwannoma. This case series highlights the variable presentation of intraocular schwannoma and how they masquerade as other choroidal tumors.

摘要

施万细胞瘤是一种罕见的良性肿瘤,在身体其他部位更常见于产生髓磷脂的周围神经,而在眼内很少见。在本报告中,我们描述了两名成年患者,他们表现为脉络膜肿块病变和新生血管性青光眼,接受了眼球摘除术,临床鉴别诊断为脉络膜黑色素瘤和脉络膜血管瘤。组织病理学证实为脉络膜施万细胞瘤。该病例系列突出了眼内施万细胞瘤的多样表现以及它们如何伪装成其他脉络膜肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fb/6561046/8ab46fc911dc/OJO-12-125-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fb/6561046/5f981fed3b83/OJO-12-125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fb/6561046/8ab46fc911dc/OJO-12-125-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fb/6561046/5f981fed3b83/OJO-12-125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98fb/6561046/8ab46fc911dc/OJO-12-125-g002.jpg

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本文引用的文献

1
Choroidal schwannoma: a case series of five patients.脉络膜神经鞘瘤:五例患者的病例系列。
Br J Ophthalmol. 2014 Aug;98(8):1096-100. doi: 10.1136/bjophthalmol-2014-304976. Epub 2014 Apr 23.
2
Choroidal schwannoma in a 6-month-old girl.
J AAPOS. 2014 Apr;18(2):197-9. doi: 10.1016/j.jaapos.2013.11.017.
3
Intraocular schwannoma.眼内施万细胞瘤。
Surv Ophthalmol. 2013 Jan-Feb;58(1):77-85. doi: 10.1016/j.survophthal.2012.04.003. Epub 2012 Sep 14.
4
Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.抗血管内皮生长因子治疗作为一种治疗神经纤维瘤病相关肿瘤的新方法。
Cancer Res. 2010 May 1;70(9):3483-93. doi: 10.1158/0008-5472.CAN-09-3107. Epub 2010 Apr 20.
5
A choroidal schwannoma confirmed by surgical excision.经手术切除证实的脉络膜神经鞘瘤。
Korean J Ophthalmol. 2009 Mar;23(1):49-52. doi: 10.3341/kjo.2009.23.1.49. Epub 2009 Mar 9.
6
Choroidal schwannoma.脉络膜神经鞘瘤。
Acta Ophthalmol Scand. 2005 Dec;83(6):754-6. doi: 10.1111/j.1600-0420.2005.00517.x.
7
Ciliary body schwannoma.
Acta Ophthalmol Scand. 1999 Aug;77(4):462-6. doi: 10.1034/j.1600-0420.1999.770423.x.
8
Melanotic schwannoma of the choroid. Immunohistochemistry and electron microscopic observations.脉络膜黑色素性施万瘤。免疫组织化学及电子显微镜观察
Ophthalmology. 1994 May;101(5):843-9. doi: 10.1016/s0161-6420(94)31249-8.