恶臭假单胞菌 KT2440 已通过 HV1 认证，而非 GRAS。
Pseudomonas putida KT2440 is HV1 certified, not GRAS.
机构信息
Laboratory of Systems and Synthetic Biology, Wageningen University and Research Centre, Stippeneng 4, 6708, Wageningen, The Netherlands.
Lifeglimmer GmbH, Markelstr. 38, 12163, Berlin, Germany.
出版信息
Microb Biotechnol. 2019 Sep;12(5):845-848. doi: 10.1111/1751-7915.13443. Epub 2019 Jun 14.
Abstract
Pseudomonas putida is rapidly becoming a workhorse for industrial production due to its metabolic versatility, genetic accessibility and stress-resistance properties. The P. putida strain KT2440 is often described as Generally Regarded as Safe, or GRAS, indicating the strain is safe to use as food additive. This description is incorrect. P. putida KT2440 is classified by the FDA as HV1 certified, indicating it is safe to use in a P1 or ML1 environment.
摘要
铜绿假单胞菌由于其代谢多样性、遗传可及性和抗应激特性，迅速成为工业生产的得力工具。铜绿假单胞菌菌株 KT2440 通常被描述为“一般认为是安全的”，或 GRAS，这表明该菌株可以安全地用作食品添加剂。这种描述是不正确的。铜绿假单胞菌 KT2440 被 FDA 归类为 HV1 认证，表明其可以在 P1 或 ML1 环境中安全使用。
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