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体外 ELF-EMF 和 RF-EMF 研究中，细胞活力对暴露时间的显著依赖性。

Significant Cellular Viability Dependence on Time Exposition at ELF-EMF and RF-EMF In Vitro Studies.

机构信息

CTB (CTB-UPM) Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Spain.

Escuela Técnica Superior de Ingenieros de Telecomunicación, Universidad Politécnica de Madrid, 28040 Madrid, Spain.

出版信息

Int J Environ Res Public Health. 2019 Jun 13;16(12):2085. doi: 10.3390/ijerph16122085.

DOI:10.3390/ijerph16122085
PMID:31200435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6617398/
Abstract

The human concern about the effect of electromagnetic fields (EMFs) has changed over time from the effects produced by EMFs of extremely low frequencies (ELFs) to the effects produced by exposure to a radio frequency (RF), with concerns shifting toward EMFs due to the development of new technologies and forms of communication. Previous studies have analysed the effects produced at different frequencies without considering in detail the effect of the time of exposure. Therefore, in the present study, we analysed in vitro the effect produced by a 100 µT EMF at different ELFs and exposure times in glioblastomas, as well as the effect produced in a fibroblast by an RF-EMF of 2.54 GHz. Our results indicate a significant time dependence in cell viability of fibroblasts exposed to an RF-EMF of 2.54 GHz and a non-time-dependent effect in cell viability of glioblastomas exposed to an ELF-EMF, highlighting the possible relation between frequency and time of exposure.

摘要

人类对电磁场 (EMF) 影响的关注随着时间的推移发生了变化，从极低频电磁场 (ELF) 产生的影响转变为射频 (RF) 暴露产生的影响，这是由于新技术和通信形式的发展而产生的对电磁场的关注。以前的研究分析了不同频率产生的影响，而没有详细考虑暴露时间的影响。因此，在本研究中，我们在体外分析了在不同 ELF 和暴露时间下，100µT 电磁场对神经胶质瘤产生的影响，以及 2.54GHz 的射频-EMF 对成纤维细胞产生的影响。我们的结果表明，暴露于 2.54GHz 的射频-EMF 的成纤维细胞的细胞活力具有显著的时间依赖性，而暴露于 ELF-EMF 的神经胶质瘤的细胞活力没有时间依赖性，这突出了频率和暴露时间之间的可能关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/2f4dcf6493f4/ijerph-16-02085-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/a43607693dd7/ijerph-16-02085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/ccec5689f7a4/ijerph-16-02085-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/526745037c02/ijerph-16-02085-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/8861e3f576d7/ijerph-16-02085-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/2f4dcf6493f4/ijerph-16-02085-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/a43607693dd7/ijerph-16-02085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/ccec5689f7a4/ijerph-16-02085-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/526745037c02/ijerph-16-02085-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/8861e3f576d7/ijerph-16-02085-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1159/6617398/2f4dcf6493f4/ijerph-16-02085-g005.jpg

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引用本文的文献

[1]
The Frequency of a Magnetic Field Determines the Behavior of Tumor and Non-Tumor Nerve Cell Models.

Int J Mol Sci. 2025-2-26

[2]
The Cellular Response Is Determined by a Combination of Different ELF-EMF Exposure Parameters: A Scope Review.

Int J Mol Sci. 2024-5-7

[3]
Low-frequency magnetic field therapy for glioblastoma: Current advances, mechanisms, challenges and future perspectives.

J Adv Res. 2025-3

[4]
Design and characterisation of a cell exposure system with high magnetic field homogeneity: RILZ coils.

Front Bioeng Biotechnol. 2024-3-8

[5]
Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.

Heliyon. 2023-2-27

[6]
It is mandatory to review environmental radiofrequency electromagnetic field measurement protocols and exposure regulations: An opinion article.

Front Public Health. 2022-10-24

[7]
Integrated Micro-Devices for a Lab-in-Organoid Technology Platform: Current Status and Future Perspectives.

Front Neurosci. 2022-4-26

[8]
30 Hz, Could It Be Part of a Window Frequency for Cellular Response?

Int J Mol Sci. 2021-3-31

[9]
50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment.

MethodsX. 2020-9-26

[10]
CT2A Cell Viability Modulated by Electromagnetic Fields at Extremely Low Frequency under No Thermal Effects.

Int J Mol Sci. 2019-12-24

本文引用的文献

[1]
Effect of cell phone radiofrequency radiation on body temperature in rodents: Pilot studies of the National Toxicology Program's reverberation chamber exposure system.

Bioelectromagnetics. 2018-4

[2]
Extremely low frequency variable electromagnetic fields affect cancer and noncancerous cells in vitro differently: Preliminary study.

Electromagn Biol Med. 2018

[3]
Power frequency magnetic field promotes a more malignant phenotype in neuroblastoma cells via redox-related mechanisms.

Sci Rep. 2017-9-13

[4]
Cytotoxicity of temozolomide on human glioblastoma cells is enhanced by the concomitant exposure to an extremely low-frequency electromagnetic field (100Hz, 100G).

Biomed Pharmacother. 2017-5-24

[5]
Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study.

J Biomed Phys Eng. 2016-12-1

[6]
Effects of extremely low-frequency pulsed electromagnetic fields (ELF-PEMFs) on glioblastoma cells (U87).

Electromagn Biol Med. 2017

[7]
Effect of extremely low frequency magnetic fields on cell proliferation and gene expression.

Bioelectromagnetics. 2015-10

[8]
Exposure to 1800 MHz radiofrequency electromagnetic radiation induces oxidative DNA base damage in a mouse spermatocyte-derived cell line.

Toxicol Lett. 2013-1-18

[9]
Effects of a low-intensity electromagnetic field on fibroblast migration and proliferation.

Electromagn Biol Med. 2011-6

[10]
Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk.

Environ Health Perspect. 2010-3

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