Feki W, Ketata W, Bahloul N, Ayadi H, Yangui I, Kammoun S
Service de pneumologie de Sfax, hôpital Hédi Chaker, route Ain km 0,5, Sfax 3029, Tunisie; Université de Sfax, Sfax, Tunisie.
Service de pneumologie de Sfax, hôpital Hédi Chaker, route Ain km 0,5, Sfax 3029, Tunisie; Université de Sfax, Sfax, Tunisie.
Rev Mal Respir. 2019 Jun;36(6):707-719. doi: 10.1016/j.rmr.2018.07.010. Epub 2019 Jun 13.
Lung abscesses are necrotic cavitary lesions of the lung parenchyma. They are usually caused by anaerobic bacteria or mixed flora and typically occur after aspiration. Primary lung abscesses occur in previously healthy patients with no underlying medical disorders and are usually solitary. Secondary lung abscesses occur in patients with underlying or predisposing conditions and may be multiple. The initial diagnosis is usually made by chest radiography showing a lung cavity with an air-fluid level. Typically, the cavity wall is thick and irregular, and a surrounding pulmonary infiltrate is often present. The differential diagnosis of pulmonary cavitation is wide, including different types of possible infections, neoplasia and malformations of the bronchial tree. Management is usually based on prolonged antibiotic treatment. Failure of conservative management, manifested by the persistence of sepsis and/or other abscess complications, may necessitate drainage with invasive techniques (percutaneous, endoscopic or surgical) or open surgical removal of the lung lesion in patients with good performance status and sufficient respiratory reserve.
肺脓肿是肺实质的坏死性空洞性病变。它们通常由厌氧菌或混合菌群引起,典型地发生于误吸后。原发性肺脓肿发生在既往健康、无基础疾病的患者中,通常为单发。继发性肺脓肿发生在有基础疾病或易感因素的患者中,可能为多发。初始诊断通常通过胸部X线检查作出,显示有气液平面的肺空洞。典型情况下,空洞壁增厚且不规则,常伴有周围肺部浸润。肺空洞的鉴别诊断范围广泛,包括不同类型的可能感染、肿瘤以及支气管树的畸形。治疗通常基于长期抗生素治疗。保守治疗失败,表现为脓毒症持续存在和/或出现其他脓肿并发症时,对于身体状况良好且有足够呼吸储备的患者,可能需要采用侵入性技术(经皮、内镜或手术)进行引流,或通过开放手术切除肺部病变。