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酪蛋白磷酸肽-无定形磷酸钙和纳米羟基磷灰石预防性处理对牙釉质抗侵蚀性的影响。

Effect of CPP-ACPF and Nano-hydroxyapatite Preventive Treatments on the Susceptibility of Enamel to Erosive Challenge.

作者信息

Dionysopoulos Dimitrios, Tolidis Kosmas, Sfeikos Thrasyvoulos

出版信息

Oral Health Prev Dent. 2019;17(4):357-364. doi: 10.3290/j.ohpd.a42690.

DOI:10.3290/j.ohpd.a42690
PMID:31204397
Abstract

PURPOSE

The purpose of this in vitro study was to evaluate the effect of two preventive clinical treatments on bovine enamel susceptibility after erosive challenge induced by a soft drink.

MATERIALS AND METHODS

Eighteen sound bovine incisors were used for this study. Three experimental groups were assigned as follows: Group 1 was the control group; Group 2 specimens received a CPP-ACPF paste treatment; and Group 3 specimens received a treatment with a product containing 1% nano-hydroxyapatite and 455 ppmF-. The specimens were submitted to erosive challenge using a common soft drink (Coca Cola). The erosive activity on the enamel was evaluated by measuring surface microhardness change (Vickers method), surface roughness alterations and surface loss (vertical scanning interferometry (VSI) method). The data were statistically analysed using one-way analysis of variance (ANOVA) and Tukey's post-hoc test at a level of statistical significance a = 0.05.

RESULTS

The tested treatments exhibited significantly lower decreases in surface microhardness compared to the control group after the erosive challenge (p < 0.05). The tested treatment groups did not show statistically significant lower increases in surface roughness compared to the control group (p > 0.05). In addition, the treatment groups exhibited statistically significant lower surface loss than the control group (p < 0.05).

CONCLUSION

Although the tested treatments reduced erosive activity, none of them provided complete protection against the development of enamel erosion, which means that they should be only used as a part of an individually tailored preventive programme.

摘要

目的

本体外研究旨在评估两种预防性临床治疗对软饮料引起的侵蚀性挑战后牛牙釉质敏感性的影响。

材料与方法

本研究使用了18颗完好的牛切牙。将其分为三个实验组,具体如下:第1组为对照组;第2组样本接受了酪蛋白磷酸肽 - 无定形磷酸钙氟化物(CPP - ACPF)糊剂治疗;第3组样本接受了含有1%纳米羟基磷灰石和455 ppm氟离子(F - )的产品治疗。使用普通软饮料(可口可乐)对样本进行侵蚀性挑战。通过测量表面显微硬度变化(维氏硬度法)、表面粗糙度改变和表面损失(垂直扫描干涉测量法(VSI))来评估牙釉质上的侵蚀活性。使用单因素方差分析(ANOVA)和Tukey事后检验对数据进行统计学分析,统计学显著性水平α = 0.05。

结果

与对照组相比,在侵蚀性挑战后,测试治疗组的表面显微硬度下降显著更低(p < 0.05)。与对照组相比,测试治疗组在表面粗糙度增加方面未显示出统计学上的显著降低(p > 0.05)。此外,治疗组的表面损失比对照组显著更低(p < 0.05)。

结论

尽管测试治疗降低了侵蚀活性,但它们均未提供对牙釉质侵蚀发展的完全保护,这意味着它们仅应用作个体化定制预防方案的一部分。

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